Results 181 to 190 of about 2,672 (202)
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1999
Abstract Nebulette is a petite nebulin isoform at the Z line region of cardiac myofibril in cardiac muscle. This 107 kDa protein consists of 22 nebulin modules bracketed by a unique N-terminal domain and C-terminal Src homology (SH3) domain. It bears a striking resemblance to the C-terminal region of skeletal muscle nebulin.
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Abstract Nebulette is a petite nebulin isoform at the Z line region of cardiac myofibril in cardiac muscle. This 107 kDa protein consists of 22 nebulin modules bracketed by a unique N-terminal domain and C-terminal Src homology (SH3) domain. It bears a striking resemblance to the C-terminal region of skeletal muscle nebulin.
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A physiological role for titin and nebulin in skeletal muscle
Nature, 1986Production of active force in skeletal muscle results from the interaction of myosin-containing thick filaments with actin-containing thin filaments. These muscles are also passively elastic, producing forces that resist stretch independently of ATP splitting or of interaction between the filaments.
R, Horowits +3 more
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Assembly of nebulin into the sarcomeres of avian skeletal muscle
Cell Motility and the Cytoskeleton, 1996In developing muscle, relatively little is known about the synthesis and incorporation of the large actin binding protein, nebulin, into the sarcomere. To determine the temporal pattern of nebulin assembly into the myofibrils of differentiating skeletal muscle cells, myofibril assembly was examined by immunofluorescence microscopy.
C L, Moncman, K, Wang
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Nebulin The Nebulous, Multifunctional Giant of Striated Muscle
Trends in Cardiovascular Medicine, 2003Nebulin is a giant, modular sarcomeric protein and although it was discovered over 2 decades ago, it remains one of the most nebulous components of striated muscle. Previously, several groups identified nebulin as the prime candidate molecule for functioning as a "ruler" to specify the precise lengths of the actin (thin) filaments in skeletal muscle ...
Abigail S, McElhinny +3 more
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Immunocytochemical study of nebulin in Duchenne muscular dystrophy
Neurology, 1988We used antibodies to nebulin in immunocytochemical studies. In normal muscle, nebulin was localized at the I band. The protein was also present in most fibers from all 15 Duchenne muscular dystrophy (DMD) patients studied, including patients who seemed to lack nebulin in electrophoretic gels and patients who demonstrated deletions of DNA in the region
Bonilla E +8 more
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Nebulin and nebulin-related proteins in striated muscle
Advances in Biophysics, 1996R, Horowits +3 more
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Expression of multiple nebulin isoforms in human skeletal muscle and brain
Muscle and Nerve, 2012Jenni Laitila +2 more
exaly
Nebulin regulates thin filament length, contractility, and Z-disk structure in vivo
EMBO Journal, 2006Christian C Witt +2 more
exaly