Results 61 to 70 of about 5,232 (145)

A review of nebulized drug delivery in COPD

, 2016
Donald P Tashkin Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA Abstract: Current guidelines recommend inhaled pharmacologic therapy as the preferred route of administration for treating COPD. Bronchodilators
Tashkin DP
core  

Evaluation of Clinical Efficacy of Intravenous Glyco-P® (Glycopyrrolate)

, 2017
Background: Glycopyrrolate has been widely used globally as an adjunct in anesthesia since early 1970’s. However, this agent has never been used in Thailand until recent introduction of the Glyco-P® (0.2 mg IV glycopyrrolate). The clinical efficacy and
Nattawut Maneekut, Prasert Sawasdiwipachai, Sukanya Dejarkom, Karuna Phatangjaijing, Sirilak Suksompong, Sathit Chairattanavanich   +5 more
core   +1 more source

UEG Week 2018 Poster Presentations

, 2018
United European Gastroenterology Journal, Volume 6, Issue S8, Page A135-A747, October 2018.
wiley   +1 more source

Efficacy and safety of twice-daily glycopyrrolate in patients with stable, symptomatic COPD with moderate-to-severe airflow limitation: the GEM1 study

, 2016
Craig LaForce,1 Gregory Feldman,2 Selwyn Spangenthal,3 Joerg H Eckert,4 Michelle Henley,5 Francesco Patalano,4 Peter D’Andrea5 1North Carolina Clinical Research, Raleigh, NC, USA; 2South Carolina Pharmaceutical Research, Spartanburg, SC, USA ...
Eckert JH, Patalano F, Spangenthal S, D’Andrea P, Feldman G, Henley M, LaForce C   +6 more
core  

Histological Assessment of Respiratory Tract and Liver of BALB/c Mice Nebulized with Tocilizumab

Pulmonary drug delivery offers a minimally invasive and efficient method for treating lung conditions, leveraging the lungs’ extensive surface area and blood flow for rapid drug absorption.
Henriquez-Camacho, César, García, Almudena, Ferreiro, Sergio, Andrés Gamazo, Paloma Jimena de, Flores, Ángela   +4 more
core   +1 more source

Comparative Characterization of Lung Muscarinic Receptor Binding After Intratracheal Administration of Tiotropium, Ipratropium, and Glycopyrrolate

, 2011
The aim of the current study was to characterize comparatively the binding of muscarinic receptor in the lung of rats intratracheally administered anticholinergic agents (tiotropium, ipratropium, glycopyrrolate) used clinically to treat chronic ...
Shizuo Yamada, Masaki Ogoda, Ryo Niiya, Tadatsura Koshika   +3 more
core   +1 more source

Investigation of potential neuropharmacological activity of neostigmine‐glycopyrrolate for intraoperative neural monitoring in thyroid surgery

, 2022
Intraoperative neuromonitoring (IONM) is frequently used in thyroid surgery to reduce recurrent laryngeal nerve injury. The use of neuromuscular blockade agent to facilitate tracheal intubation, is a common cause of IONM failure.
Tzu‐Yen Huang, Hoon Yub Kim, Young Jun Chai, Jung‐Man Lee, Dongwook Won, Gianlorenzo Dionigi, Moon Young Oh, Miyeon Seo, Hyun Suk Choi, Che‐Wei Wu   +9 more
core   +1 more source

A case report: Glycopyrrolate for treatment of exercise-induced hyperhidrosis

, 2017
Objective: Hyperhidrosis can cause dehydration and exercise intolerance. There are several case reports of extremely high sweat rates in athletes. We present as case report of a 17-year-old male with the highest sweat rate recorded in the literature (5.8
Britt Marcussen, Matthew Jepson, Daniel Bonthius, Andrew Peterson, Christopher Anthony, Daniel Pelzer, Matthew Negaard   +6 more
core   +2 more sources

The Effect of Glycopyrrolate on Nocturnal Sialorrhea in Patients Using Clozapine: A Randomized, Crossover, Double-Blind, Placebo-Controlled Trial [PDF]

, 2017
BACKGROUND: Nocturnal sialorrhea is one of the most frequent adverse events in clozapine treatment. Symptomatic management of sialorrhea usually consists of off-label treatment with anticholinergic agents.
Ingeborg Wilting, Wilting, Ingeborg, Colen-de Koning, Jantine C A, Schulte, Peter F J, Eibert R. Heerdink, Heerdink, Rob, van Haelst, Ingrid M M, Doodeman, Hieronymus J., Jantine C.A. Colen–de Koning, Afd Pharmacoepi & Clinical Pharmacology, Pharmacoepidemiology and Clinical Pharmacology, Toine C.G. Egberts, Egberts, T.C.G., Heerdink, Eibert R, Wiepke Cahn, Cahn, Wiepke, Peter F.J. Schulte, Hieronymus J. Doodeman, Doodeman, Hieronymus J, Haelst,van, Ingrid, Man, Wai Hong, Egberts, Toine C G, Wai Hong Man, Ingrid M.M. van Haelst, Colen–de Koning, Jantine, Schulte, Peter F.J   +25 more
core   +1 more source

Additional file 1 of Dose selection for glycopyrrolate/eFlow® phase III clinical studies: results from GOLDEN (Glycopyrrolate for Obstructive Lung Disease via Electronic Nebulizer) phase II dose-finding studies

, 2017
Online Supplementary Data. Table S1. Patient demographics and baseline characteristics, GOLDEN 2 (ITT population). Table S2. Patient demographics and baseline characteristics, GOLDEN 6 (safety population). Table S3. Change from baseline in trough FEV1 on Day 7 and Day 28, GOLDEN 2 (ITT population). Table S4. Change from baseline in trough FEV1 on Day 7,
Donohue, James, Goodin, Thomas, Tosiello, Robert, Wheeler, Alistair   +3 more
openaire   +1 more source