Results 101 to 110 of about 2,053 (202)

Structure‐based discovery of thiamine uptake inhibitors

British Journal of Pharmacology, Volume 182, Issue 22, Page 5611-5626, November 2025.
Background and Purpose Thiamine (vitamin B1) is an essential coenzyme and catalyses various reactions in central metabolic pathways. Since mammals have lost the ability to synthesise thiamine de novo, this micronutrient has to be imported via the high affinity solute carriers SLC19A2 and A3 across the plasma membrane.
Florian Gabriel, Björn Windshügel, Christian Löw   +2 more
wiley   +1 more source

Inhaled biologics for respiratory diseases: clinical potential and emerging technologies. [PDF]

Drug Deliv Transl Res
Shaibie NA, Mohammad Faizal NDF, Buang F, Srichana T, Mohd Amin MCI.   +4 more
europepmc   +1 more source

Fatigue‐Life Prediction of Additively Manufactured Material: Effects of Defect Spacing and Multi‐Site Damage

Fatigue &Fracture of Engineering Materials &Structures, Volume 48, Issue 11, Page 4860-4878, November 2025.
ABSTRACT Fatigue‐life prediction of additively manufactured metals is challenging due to the random distribution of process‐induced defects, whose proximity can significantly influence crack initiation and propagation, and whose multiplicity can promote multi‐site damage.
Leah Buiter, Aref Yadollahi, James C. Newman Jr.   +2 more
wiley   +1 more source

Impact of nebulizers on nanoparticles-based gene delivery efficiency: <i>in vitro</i> and <i>in vivo</i> comparison of jet and mesh nebulizers using branched-polyethyleneimine. [PDF]

Drug Deliv
Ghanem R, Buin X, Haute T, Philippe J, Kaouane G, Leclerc L, Guivarch M, Le Gall T, Pourchez J, Montier T.   +9 more
europepmc   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, Volume 19, Issue 10, Page 2882-2904, October 2025.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

External Jet Nebulization and Measured Ventilator Performance-Is It Time to Change Things Up? [PDF]

Respir Care
Davis MD.
europepmc   +1 more source

Choosing nasal devices: a dilemma in clinical practice. [PDF]

Acta Biomed, 2023
Varricchio A, Brunese F, La Mantia I, Ascione E, Ciprandi G.   +4 more
europepmc   +1 more source

Solvent‐Free Fabrication Methods of Metal Halide Perovskites

Advanced Materials, Volume 37, Issue 40, October 9, 2025.
This review explores the current status of solvent‐free fabrication methods of metal halide perovskites, such as thermal evaporation, magnetron sputtering, pulsed laser deposition, e‐beam and atomic layer deposition, solid phase growth, and laser printing.
Ran Ji, Arindam Mallick, Boris Rivkin, Hurriyet Yuce‐Cakir, Oana D. Jurchescu, Yana Vaynzof   +5 more
wiley   +1 more source

Reassessing the Role of Heated Humidification During Nebulization: Implications for Clinical Practice. [PDF]

Respir Care
Li J.
europepmc   +1 more source

Aerosolization Performance of Immunoglobulin G by Jet and Mesh Nebulizers. [PDF]

AAPS PharmSciTech, 2023
Chang KH, Park BJ, Nam KC.
europepmc   +1 more source