Results 71 to 80 of about 2,153 (200)

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

A new branch of mammalian vitamin B6 metabolism: AKR1C‐mediated conversion of pyridoxal to pyridoxine and 4‐pyridoxolactone

The FEBS Journal, EarlyView.
Pyridoxal 5′‐phosphate (PLP) homeostasis relies on salvage enzymes, yet key metabolic branches remain undefined. We identify AKR1C isozymes as previously undescribed contributors that convert pyridoxal into pyridoxine or 4‐pyridoxolactone through reductase and dehydrogenase activities.
Nayu Kito, Yasuyuki Kitaura, Kyoka Iino, Kazuya Toriumi, Hyunah Noh, Naoya Ogawa, Makoto Arai, Hisashi Hemmi, Tomokazu Ito   +8 more
wiley   +1 more source

Embedded Pesticide Use: Exploring the Pesticide‐Land Nexus

Journal of Agrarian Change, EarlyView.
ABSTRACT Since the turn of the century, global land grabs, farmland financialization and land‐based food sovereignty movements have returned the land question to the heart of agrarian studies. Meanwhile, abiding interest in pesticides has been reanimated in the face of changes in production, regulation and knowledge of toxicity.
Julie Guthman, Marion Werner
wiley   +1 more source

Effects of autoclave sterilization on the dimensional stability of implant surgical guides: A 3D in vitro analysis

Journal of Prosthodontics, EarlyView.
Abstract Purpose Surgical guides are medical devices used in static implant surgery to replicate the prosthetic and surgical implant position planned with computer‐assisted software before surgery. Their use reduces invasiveness and improves safety and outcomes of implant surgery, provided that their accuracy is ensured from design to manufacturing and
Lucio Lo Russo, Pierluigi Mariani, Carlo Ercoli, Giusy Caprio, Ji‐Man Park, Luigi Laino, Fariba Esperouz   +6 more
wiley   +1 more source

Vertical profiling of shock attenuation at the Rochechouart impact structure, France

Meteoritics &Planetary Science, EarlyView.
Abstract Rochechouart, south‐west France, is a complex impact structure. Here, we present the first report of shock barometry of quartz from what are likely parautochthonous basement units at depth, based on samples from the 2017 C.I.R.I.R drilling campaign. The crystallographic orientations of 725 sets of PDFs in 512 quartz grains in samples from four
P. Struzynska, S. Alwmark, C. Alwmark, M. H. Poelchau, P. Lambert   +4 more
wiley   +1 more source

Fucosylation limits ADCC in clinically used anti‐RhD monoclonal antibodies

Transfusion, EarlyView.
Abstract Background Haemolytic disease of the fetus and newborn (HDFN) is caused by maternal alloantibodies, often targeting the D antigen on fetal red blood cells. Maternal immunization is preventable with timely administration of anti‐D polyclonal antibodies (pAbs).
Gabriela Koike, Albert Bondt, Douwe Schulte, Rien Leuvenink, Dirk Jan Mons, Peter C. Ligthart, E. Joanne T. Verweij, AFRICARhE Consortium, Enrico Lopriore, E. J. T. Joanne Verweij, Tienke Vermeiden, Thomas van den Akker, C. Ellen van der Schoot, Derek P. de Winter, Renske van Oever, Abera Kenay Tura, Tadesse Gure, Assefa Desalew, Tewodros Tesfa, Konjit Eshetu, Jeremia Pyuza, Rafiki N. Mjema, Priscus John Mapendo, Jeremiah John Hhera, Bariki Mchome, Patricia Swai, Blandina T. Mmbaga, Aisa Shayo, Peter Moons, Kondwani Kawaza, Luis Gadama, Albert J. R. Heck, C. Ellen van der Schoot, Gestur Vidarsson   +33 more
wiley   +1 more source

The effects of a (poly)phenol‐rich food intervention on markers of exercise‐induced inflammation and oxidative stress: A randomised controlled trial

Experimental Physiology, EarlyView.
Abstract This study examined whether consuming a (poly)phenol‐rich food before strenuous muscle‐damaging exercise can modify post‐exercise markers of inflammation and oxidative stress. Using a double‐blinded, randomised, placebo‐controlled, between‐subjects design, 26 recreationally active males (n = 15) and females (n = 11) consumed higher‐(poly ...
Abrar Al Hebshi, Josh Thorley, Ana Rodriguez‐Mateos, Zicheng Zhang, Lewis J James, Tom Clifford   +5 more
wiley   +1 more source

Fast and Sensitive Measurement of Off‐Flavors in Recirculating Aquaculture Systems

Rapid Communications in Mass Spectrometry, Volume 40, Issue 15, 15 August 2026.
ABSTRACT Rationale Geosmin and 2‐methylisoborneol (2‐MIB) are odor‐active compounds responsible for earthy off‐flavors in fish, creating significant quality concerns in recirculating aquaculture systems (RAS). Their extremely low odor thresholds make rapid and highly sensitive detection essential for maintaining product quality and consumer acceptance ...
Pedro Martínez Noguera, Sylvester Holt, Raju Podduturi, Wender L. P. Bredie, Jonathan D. Beauchamp, Mikael A. Petersen   +5 more
wiley   +1 more source

Zinc Oxide Nanoparticles for Food Applications: From Synthesis and Functional Properties to Safety and Sustainability

Food Frontiers, Volume 7, Issue 4, July 2026.
Green and conventional synthesis routes produce ZnO nanoparticles with tunable physicochemical properties for food applications, ZnO‐NPs enhance antimicrobial activity, UV protection, and food preservation through ROS generation and ZN2+ release. However, particle dissolution, migration, cytotoxicity, and environmental concerns highlight the need for ...
Liza Akter, Md. Hassan Bin Nabi, Yusuf Chowdhury, Mohima Akther Any, Md Abu Rayhan, Abid Hassan Arnab, Wahidu Zzaman   +6 more
wiley   +1 more source

Chinese Society of Pediatric Anesthesiology Guideline for Pediatric Sedation (2025)

Pediatric Anesthesia, Volume 36, Issue 7, Page 850-871, July 2026.
ABSTRACT Background With the increasing variety of pediatric diagnostic procedures, a growing number of children require sedation for diagnostic examinations. Appropriate sedation protocols guarantee the safety of children during sedation and improve its efficiency.
Xingrong Song, Dongxu Lei, Yu Cui, Zhen Du, Yingping Jia, Yue Jin, Hang Tian, Ying Xu, Lifang Yang, Jianmin Zhang, Jijian Zheng, Yunxia Zuo, Liang Zhong, John Zhong, Maryrose Osazuwa, Elizabeth Drum, Charles Dean Kurth, Yue Huang, Qinghua Huang, Heqi Liu, Wei Liu, Rui Ma, Dongpi Wang, Tingting Wang, Zixin Wang, Siwei Wei, Lei Yang, Rui Zhou, Liumei Chen, Weifeng Yu, Jun Li, Mazhong Zhang, Li Zhang, Shuangquan Qu, Shoudong Pan, Rong Wei, Liming Cheng, Yaolong Chen, Xueping Li, Zhenyu Tang   +39 more
wiley   +1 more source