Results 141 to 150 of about 231,445 (248)

Assessing the Number of Components in Mixture Models: a Review. [PDF]

Despite the widespread application of finite mixture models, the decision of how many classes are required to adequately represent the data is, according to many authors, an important, but unsolved issue.
Ana Oliveira-Brochado, Francisco Vitorino Martins   +1 more
core  

Targeting necroptosis protects against astrocyte death and hippocampal sclerosis in experimental temporal lobe epilepsy

The Journal of Physiology, EarlyView.
Abstract figure legend Experimentally induced status epilepticus induces microglial TNFα release, which binds to astrocytic TNFR1 and triggers activation of RIPK1/RIPK3/MLKL signalling, initiating necroptotic astrocytic death that contributes to the development of hippocampal sclerosis. Created with Biorender.com.
Zhou Wu, Lukas Henning, Christian Steinhäuser, Peter Bedner   +3 more
wiley   +1 more source

Conversion Surgery after Chemotherapy in a Stage IV BRAF V600E‐Mutated Laterally Spreading Tumor With Neuroendocrine Component

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT We report a rare case of a BRAF V600E‐mutated laterally spreading tumor, granular type (LST‐G), with a neuroendocrine carcinoma (NEC) component in a patient with stage IV colorectal cancer. The patient presented with multiple lymph nodes and liver metastases.
Reona Kawamura, Naoya Toyoshima, Masau Sekiguchi, Hiroyuki Takamaru, Masayoshi Yamada, Nozomu Kobayashi, Hidekazu Hirano, Yasuyuki Takamizawa, Taiki Hashimoto, Yutaka Saito   +9 more
wiley   +1 more source

Human Milk–Derived Peptide MAMP‐1 Ameliorates Sepsis‐Associated Acute Lung Injury in Mice Through APOA4 and the TLR4/NF‐κB Signaling Pathway

Food Frontiers, Volume 7, Issue 2, March 2026.
The study found that MAMP‐1 can alleviate lung injury by modulating the TLR4 signaling pathway to suppress LPS‐induced inflammation and promote cholesterol reverse transport. ABSTRACT Sepsis‐associated acute lung injury (SALI) significantly jeopardizes the health and survival prospects of neonates.
Shimei Lu, Rui Long, Yanmin Li, Fengqiong Tan, Xiaoguang He, Tengfei Wang, Xingyun Wang, Fengdan Xu, Ning Li   +8 more
wiley   +1 more source

Novel therapeutic strategy targeting STMN1 using chlorambucil‐conjugated pyrrole–imidazole polyamide in small cell lung cancer

International Journal of Cancer, Volume 158, Issue 5, Page 1336-1347, 1 March 2026.
What's New? Small cell lung cancer (SCLC) is aggressive and difficult to treat but exhibits high levels of stathmin 1 (STMN1), a candidate therapeutic target. In this study, the authors synthesized a chlorambucil (Chb)‐conjugated pyrrole–imidazole polyamide (PIP) compound targeting the STMN1 promoter and DNA sequences and evaluated its efficacy in ...
Ryohei Yoshikawa, Takayoshi Watanabe, Yoichi Ohtaki, Toshikazu Bando, Hiroshi Sugiyama, Takuya Araki, Hideaki Yashima, Bilguun Erkhem‐Ochir, Haruka Okami, Gendensuren Dorjkhorloo, Ikuma Shioi, Toshiteru Nagashima, Natsuko Kawatani, Tomohiro Yazawa, Eiji Narusawa, Takayuki Kosaka, Osamu Kawashima, Mitsuhiro Kamiyoshihara, John D. Minna, Luc Girard, Ken Shirabe, Hiroki Nagase, Kimihiro Shimizu, Takehiko Yokobori   +23 more
wiley   +1 more source

Pigeons, portals, and Pacman: Insightful problem solving and navigation using a touchscreen video game

Journal of the Experimental Analysis of Behavior, Volume 125, Issue 2, March 2026.
Abstract Video games have been used in several studies to investigate problem solving. We present empirical findings from a redesigned touchscreen navigation “grid‐world” procedure resembling the classic video game PacMan (hereafter, “pacman”) played by pigeons. Our objective was to develop a procedure to study insight, similar to that of Epstein et al.
Rafael S. Rodrigues, Cyrus Kirkman, Miriam Garcia‐Mijares, Aaron P. Blaisdell   +3 more
wiley   +1 more source

A Retrospective Study on the Clinicopathological Characteristics and Prognostic Analysis of Gynecologic Neuroendocrine Carcinoma. [PDF]

Cancer Med
Ren Y, Li S, Xiang S, Xu J.
europepmc   +1 more source

Five‐Minute Apgar Scores and Its Prognostic Value for Mortality and Severe Morbidity in Very Preterm Infants: A Multinational Cohort Study

BJOG: An International Journal of Obstetrics &Gynaecology, Volume 133, Issue 4, Page 649-659, March 2026.
ABSTRACT Objective To examine associations between a 5‐min Apgar score < 7 and severe neonatal outcomes in very preterm (VPT) infants and how results are impacted by variations in assigning Apgar scores within an international context. Design Prospective observational population‐based cohort study.
Harald Ehrhardt, Soodabeh Behboodi, Rolf F. Maier, Adrien M. Aubert, Ulrika Åden, Elizabeth S. Draper, Anna Gudmundsdottir, Veronica Siljehav, Heili Varendi, Tom Weber, Michael Zemlin, Jennifer Zeitlin, on behalf of the EPICE/SHIPS Research Group, J. Lebeer, P. Van Reempts, E. Bruneel, E. Cloet, A. Oostra, E. Ortibus, I. Sarrechia, K. Boerch, L. Huusom, P. Pedersen, T. Weber, A. Hasselager, L. Toome, H. Varendi, M. Männamaa, P. Y. Ancel, A. Burguet, P. H. Jarreau, V. Pierrat, P. Truffert, R. F. Maier, M. Zemlin, B. Misselwitz, S. Schmidt, L. Wohlers, M. Cuttini, D. Di Lallo, G. Ancora, D. Baronciani, V. Carnielli, I. Croci, G. Faldella, F. Ferrari, F. Franco, G. Gargano, A. van Heijst, C. Koopman‐Esseboom, J. Gadzinowski, J. Mazela, A. Montgomery, T. Pikuła, H. Barros, R. Costa, L. Mendes Graça, M. do Céu Machado, C. Rodrigues, T. Rodrigues, U. Aden, A. K. Edstedt Bonamy, M. Norman, E. S. Draper, E. M. Boyle, A. Fenton, S. J. Johnson, B. N. Manktelow, D. W. A. Milligan, S. Mader, N. Thiele, J. Walz, S. Petrou, J. Zeitlin, M. Bonet, C. Bonnet, R. El Raffei, A. Piedvache, A. V. Seppanen, A. M. Aubert   +79 more
wiley   +1 more source

Prevalence of neonatal necrotizing enterocolitis and predictors in Ethiopia: a systematic review and meta-analysis. [PDF]

Int Health
Balis B, Lami M, Musa I, Jibro U, Birhanu A, Yadeta TA.   +5 more
europepmc   +1 more source

Modification and verification of an antenna design for Petite Amateur Navy Satellite (PANSAT) using NEC

, 1995
In this thesis, a tangential turnstile antenna is modified and verified for the Petite Amateur Navy Satellite (PANSAT). The Numerical Electromagnetics Code (NEC) is used to model the antenna system. The final design provides a circularly polarized, omnidirectional radiation pattern with maximum nulls of -2.7 dRi.
openaire   +1 more source