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The immunogenicity of hookworm (Necator americanus) acetylcholinesterase (AChE) in man
Parasite Immunology, 1993SummaryA number of different but complementary approaches have been used to demonstrate the immunogenicity of Necator americanus acetylcholinesterase to infected individuals. Western blotting of parasite somatic extracts with human postâinfection sera and a specific rabbit antiserum to AChE resulted in the development of almost identical antigen ...
D I Pritchard
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Genes and genomes of Necator americanus and related hookworms
International Journal for Parasitology, 2000The human hookworms (Necator americanus and Ancylostoma duodenale) infect over one billion people. The phylogenetic relationships of the human hookworms suggest independent acquisition of the human host. The hookworms probably have a haploid chromosome number n = 6, and an XX-XO sex determination mechanism is likely to be used.
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A simple method for the collection of Necator americanus larvae
Journal of Helminthology, 1989ABSTRACTA simple method for the collection of third-stage larvae of Necator americanus has been described. This technique provides repeated recovery of very clean larvae from cultures in moderate numbers.
J, Mueller +4 more
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The specificity of the human IgE response to Necator americanus
Parasite Immunology, 1995SUMMARYHuman IgE responses to helminth infections have been described as both problematic and beneficial, in that type 1 hypersensitivity to parasite infections can reputedly cause pathology and/or parasite expulsion, (Pritchard, Quinnell & Walsh 1995).
D I, Pritchard, E A, Walsh
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Hookworm (Necator americanus) infection and storage iron depletion
Transactions of the Royal Society of Tropical Medicine and Hygiene, 1991The relationship between iron status and the intensity of infection with hookworm was investigated in a rural population on Karkar Island, Mandang Province, Papua New Guinea. There was a significant negative correlation between plasma ferritin level and hookworm burden, which was strongest in males.
Pritchard, D. I. +7 more
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Secretion of Metalloproteases by Living Infective Larvae of Necator americanus
The Journal of Parasitology, 1992Fresh living third-stage larvae of Necator americanus released a significant amount of label within 2 hr of their incubation on 125I-labeled gelatin-coated polystyrene plastic plates. This protease activity was primarily susceptible to o-phenanthroline, which identifies the activity as predominantly metalloprotease.
S, Kumar, D I, Pritchard
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Site of resistance to Necator americanus in hamsters.
Acta tropica, 1986Resistance to the development of human hookworm, Necator americanus was examined in 3- to 6-week-old young adult hamsters. Only 3% of N. americanus infective third stage larvae (NaL3) reached maturity in the intestines of young adults as opposed to as many as 60% in 2-day-old baby hamsters. This seemingly effective resistance prevailing in young adults
G R, Rajasekariah +3 more
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The exsheathment of Necator americanus infective larvae.
The Southeast Asian journal of tropical medicine and public health, 2007Infective 3rd-stage larvae of Necator americanus were treated with human sweat under various conditions, and compared with human serum, 1.5% saline solution, and distilled water. The infective larvae were observed under inverted microscopy. The highest percentage (14.0%) of the exsheathed larvae was found in human sweat after 2 hours' incubation at 37 ...
Sataporn, Pasuralertsakul +1 more
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Necator americanus: Activity patterns in the egg and the mechanism of hatching
Experimental Parasitology, 1974Abstract Necator americanus developed normally in distilled water and in solutions of up to 4% NaCl, hatching however, occurred only in the lower tonicities. Together with other observations, this led to the conclusion that, as with many other nematodes, osmotic changes were critical for emergence.
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Necator americanusand the Domestic Pig
Journal of Helminthology, 1923The occurrence of Ankylostomes resembling human hookworms in the domestic pig has been the subject of several recent papers, the most noteworthy being the contributions of Ackert and Payne (1922 and 1923) and Gordon (1922 and 1923).
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