Results 91 to 100 of about 641,347 (268)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Механизм формирования эффективной материальной мотивации персонала

open access: yesПутеводитель предпринимателя, 2020
The article concerns various components of material motivation. It focuses on main material incentives which impact efficiency of labour. Authour presents results of research of a company’s staff which can be usefull in development of effective system of

doaj  

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

EU vs Local Market Orientation: Western Balkan Entrepreneur's Challenge

open access: yesEntrepreneurial Business and Economics Review, 2019
Objective: The main objective of the article is to analyse the relationship between entrepreneurs’ profiles and their market orientation, i.e. to compare two groups of entrepreneurs – opportunity entrepreneurs and necessity entrepreneurs
Gazmend Qorraj, Gezim Jusufi
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

THE NECESSITY OF EDUCATION:

open access: yes, 2013
In his essay, “Ideology and the Ideological State Apparatus,”1 Althusser proclaims the educational apparatus to have become what the church or religious apparatus was in the Middle Ages. That is to say, the educational apparatuses are the ones where people are more effectively than anywhere else subjected to becoming subjects ...
openaire   +1 more source

Is it accidental? Unfinished argument about one eternal philosophical problem

open access: yesИнтеллект. Инновации. Инвестиции, 2019
The purpose of this article is determining the chance's role to play in the modern scientific picture of the world. The origins research of this issue go back to the antique-style: to the Democritus's picture of the world, in which there is no place for ...
T.Z. Nazarov   +2 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

The Creative Nature of Human Life in the Light of the Ideas of the Russian Philosophers

open access: yesУправленческое консультирование, 2018
The article analyzes the understanding of the nature of creativity in the works of Russian religious philosophers. The fundamental importance of this topic for philosophical anthropology is derived from the obvious to the religious thinker circumstance ...
Vladimir Borisovich Aleksandrov
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

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