Results 71 to 80 of about 1,213,303 (253)
Le système des passions dans la tragédie lullyste. L’exemple de la fureur
Acta Universitatis Carolinae Philologica, 2018 What is the dramatic action in Lully and his librettists ’ “tragedies en musique”? We argue that it consists in the necessary deployment of a set of passions carefully articulated, according to an initially euphoric conception – some passions guarantee ...
Céline Bohnert
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito +7 more
wiley +1 more source
Necessity and Chance in Marx's Doctoral Thesis [PDF]
حکمت و فلسفهAccording to Marx's interpretation, in the Democritean system, atoms move in a vacuum according to a blind necessity. Applying the word "accidental" to the Democritus system does not imply the unpredictable or causeless movement of atoms; rather, it ...
Ali Karbasizadeh Esfahani, Milad Omrani
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Opportunity and/or necessity entrepreneurship? The impact of the socio-economic characteristics of entrepreneurs [PDF]
Few studies have tried to identify the impact of the socio-economic characteristics of entrepreneurs on their opportunity-necessity positioning. Based on a sample of 538 entrepreneurs, we point out that individuals who get involved in an entrepreneurial ...
Janssen, Frank +3 more
core
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
"Entrepreneurs out of Necessity": A Snapshot [PDF]
"Entrepreneurs out of necessity" identified by the Global Entrepreneurship Monitor survey are a sizeable group across countries. They tend to have low education, run smaller firms, expect their firms to grow less, but are likely to stay in the market ...
Poschke, Markus
core
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Factors Influencing the Entrepreneurial Engagement of Opportunity and Necessity Entrepreneurs [PDF]
This paper investigates determinants of engagement in various stages of the entrepreneurial process while considering an individual's start-up motivation using 2007 survey data for 27 European countries and the US. Next to opportunity and necessity start-
Ingrid Verheul +3 more
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source