Results 221 to 230 of about 1,213,303 (253)

Explainable Machine Learning for Early Prediction of Surgical Necessity in Gastrointestinal Emergencies: A Multimodal Diagnostic Study. [PDF]

Diagnostics (Basel)
Anca Monica OM, Venter DP, Mihai S, Oprescu C, Gabriel A, Bogdan D, Bianca-Maria M, Sebastian V, Plotogea OM, Madalina I.   +9 more
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

What influences patients' experiences of cannulation for haemodialysis performed by nursing staff? A qualitative interview study. [PDF]

J Res Nurs
Fielding C, Brand S, Bramley L, Taal M, Sorrell C, Selby NM, Buchanan H.   +6 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Advancing cross-domain integration and semantic technologies: proceedings of the 19th international symposium on integrative bioinformatics. [PDF]

J Integr Bioinform
Ebeling MA, Lange M, Weise S, Scholz U.
europepmc   +1 more source

Attitudes and practices regarding preoperative psychological evaluation in orthognathic surgery: a scenario-based national survey of Turkish oral and maxillofacial surgeons. [PDF]

BMC Oral Health
Urhan Güçlü Ş, Aydın P, Erdem MK, Önder ME, Kişnişci RŞ.   +4 more
europepmc   +1 more source

Beliefs of medicine questionnaire: Translation, validation, and adaptation for post-acute coronary syndrome patients in the south of Sulawesi population, Indonesia. [PDF]

Explor Res Clin Soc Pharm
Halid Z, Perwitasari DA, Sulistyani N, Faridah IN, Alifiar L, Nguyen T, Horne R.   +6 more
europepmc   +1 more source

Knowledge, Psychological Distress, and Medication Beliefs Among Tuberculosis Patients in Southwest China: A Mediation Analysis. [PDF]

Healthcare (Basel)
Zheng Y, Dou L, Jike C, Liao R, Yu G, Wang J, Wang R, Wang Y, Bi R, Pei R, Li Y.   +10 more
europepmc   +1 more source

Real-World Osteoporosis Pharmacotherapy in the UAE: Prescribing Trends, Adherence, and Patient Beliefs. [PDF]

Healthcare (Basel)
Alnuaimi MAA, Rabbani SA, Alnaeimi KEA, Obaid KAA, Shah SS, El-Tanani M, Alam A.   +6 more
europepmc   +1 more source