Results 71 to 80 of about 1,226,069 (315)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Low level termination of external carotid artery and its clinical significance: A case report

Archives of Clinical and Experimental Surgery, 2015
The external carotid arterial system is a complex vascular system providing nourishment to the territorial areas of the head and neck. The branches of the external carotid artery are the key landmarks for adequate exposure and appropriate placement of ...
Surekha Devadasa Shetty, Satheesha Nayak Badagabettu, Naveen Kumar, Ashwini Aithal   +3 more
doaj   +1 more source

Spatiotemporal symmetries in the disynaptic canal-neck projection [PDF]

, 2007
The vestibular system in almost all vertebrates, and in particular in humans, controls balance by employing a set of six semicircular canals, three in each inner ear, to detect angular accelerations of the head in three mutually orthogonal coordinate ...
Golubitsky, Martin, Shiau, Liejune, Stewart, Ian   +2 more
core   +1 more source

‐19 pandemic [PDF]

, 2020
The COVID‐19 pandemic has had a significant impact on many aspects of head and neck cancer (HNC) care. The uncertainty and stress resulting from these changes has led many patients and caregivers to turn to HNC advocacy groups for guidance and support ...
Tsue, Terance T., Rauscher, Erika, Caputo, Mary Ann, Ready, John, Terance T. Tsue, Yan, Flora, Moore, Michael G., Michael G. Moore, Fakhary, Carole, Amanda Hollinger, John Ready, Cherie‐Ann O. Nathan, Nathan, Cherie-Ann O., Flora Yan, Danielle Yearout, Mary Ann Caputo, Carole Fakhry, Terry A. Day, Leonardis, Chris, Erika Rauscher, Yearout, Danielle, Day, Terry A., Hollinger, Amanda, Fakhry, Carole, Chris Leonardis   +24 more
core   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Imaging of Pharyngocele: An Occupational Overuse Syndrome

Oman Medical Journal, 2020
Pharyngocele is a rare pathology of the pharynx caused by the laxity of the thyrohyoidmembrane. Only about 60 true lateral pharyngocele cases have been reported in the literature over the last 133 years.
Dillibabu Ethiraj, Suresh D. Kumar, Venkatraman Indiran, Prabakaran Maduraimuthu   +3 more
doaj   +1 more source

Head and Neck Juxtacortical Chondrosarcoma: A Systematic Review [PDF]

, 2019
Objective: To present a case and systematically evaluate trends in clinical presentation, imaging, histopathology, and management modalities and outcomes of all head and neck juxtacortical chondrosarcoma (HNJCS) cases reported in the existing literature.
Alwani, Mohamedkazim, Summerlin, Don-John, Jones, Alexander Joseph   +2 more
core   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Abcessos parafaríngeos na criança: estudo retrospectivo de 5 anos Parapharyngeal abscess in children: five year retrospective study

Brazilian Journal of Otorhinolaryngology, 2009
Os abcessos laterofaríngeos e retrofaríngeos são infecções potencialmente fatais, designadamente na criança. OBJETIVO: Revisão de agentes etiológicos, achados clínicos e de exames de imagem de abcessos laterofaríngeos e retrofaríngeos em crianças, assim ...
Pedro Miguel dos Santos Marques, Jorge Eduardo Freitas Spratley, Laurentino Manuel Mendes Leal, Eduardo Cardoso, Margarida Santos   +4 more
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source