Results 91 to 100 of about 928,136 (402)

Polydopamine Nanohydrogel Decorated Adhesive and Responsive Hierarchical Microcarriers for Deafness Protection

Advanced Science, EarlyView.
A type of polydopamine (PDA) nanogel decorated adhesive and responsive hierarchical microcarriers for ALA delivery and deafness prevention. PDA@microcarriers can protect the encapsulated drugs from external disturbances and prolong their retention time in the inner ear.
Hong Chen, Hui Zhang, Jiayi Li, Xianmei Wei, Chenjie Yu, Yuanjin Zhao, Maoli Duan, Xiaoyun Qian, Xia Gao   +8 more
wiley   +1 more source

RONIN/HCF1‐TFEB Axis Protects Against D‐Galactose‐Induced Cochlear Hair Cell Senescence Through Autophagy Activation

Advanced Science, EarlyView.
D‐galactose (D‐gal) induced inner ear hair cell senescence by inhibiting TFEB transcription. RONIN/HCF1 promotes TFEB transcription to prevent cochlear HCs from D‐gal‐induced senescence through autophagy activation. Abstract Age‐related hearing loss is characterized by senescent inner ear hair cells (HCs) and reduced autophagy.
Yongjie Wei, Yuhua Zhang, Wei Cao, Nan Cheng, Yun Xiao, Yongjun Zhu, Yan Xu, Lei Zhang, Lingna Guo, Jun Song, Su‐hua Sha, Buwei Shao, Fang Ma, Jingwen Yang, Zheng Ying, Zuhong He, Renjie Chai, Qiaojun Fang, Jianming Yang   +18 more
wiley   +1 more source

A decrease of calcitonin serum concentrations less than 50 percent 30 minutes after thyroid surgery suggests incomplete C-cell tumor tissue removal [PDF]

, 2010
The prognosis of medullary thyroid carcinoma (MTC) depends on the completeness of the first surgical treatment. To date, it is not possible to predict whether the tumor has been completely removed after surgery.
A. Colao, A. Faggiano, American Thyroid Association Guidelines Task Force, Kloos, Costante, Dralle, Dralle, F. Milone, G. Lombardi, Gharib, Grauer, I. Ventre, Inabnet, L. Pezzullo, Leboulleux, M. G. Chiofalo, Machens, Machens, Machens, Moley, R. Giannattasio, R. Severino, Rago, Scheuba, Scollo, V. Ramundo, Wells Jr   +25 more
core   +1 more source

Pinoresinol Diglucoside Attenuates Nuclear Receptor Coactivator 4‐Mediated Ferritinophagy Associated with Cisplatin‐Induced Hearing Loss

Advanced Science, EarlyView.
Pinoresinol diglucoside, a bioactive component extracted from traditional Chinese medicine, attenuates cisplatin‐induced ototoxicity in vivo and in vitro. The protective effect is achieved by downregulation of Socs1. The present study is the first to investigate the expression and function of Socs1 in inner ear, which is known to promote ferroptosis ...
Yin Chen, Cheng Cheng, Ao Li, Dengbin Ma, Siyu Li, Handong Wang, Song Gao, Dingding Liu, Panpan Song, Chenjie Yu, Xiaoyun Qian, Guoqiang Wan, Xia Gao   +12 more
wiley   +1 more source

Accuracy of preoperative MRI to assess lateral neck metastases in papillary thyroid carcinoma [PDF]

, 2017
Primary treatment of papillary thyroid carcinoma (PTC) with lateral lymph node metastasis is surgery, but the extent of lateral neck dissection remains undefined.
Aro, Katri, Bäck, Leif, Linden, Riikka, Mäenpää, Hanna, Renkonen, Suvi, Silen, Robert, Tapiovaara, Laura   +6 more
core   +1 more source

Cost-Effectiveness Analysis of Elective Neck Dissection in Patients With Clinically Node-Negative Oral Cavity Cancer.

Journal of Clinical Oncology, 2016
Purpose Recently, a large randomized trial found a survival advantage among patients who received elective neck dissection in conjunction with primary surgery for clinically node-negative oral cavity cancer compared with those receiving primary surgery ...
Joseph R Acevedo, K. Fero, Bayard Wilson, A. Sacco, L. Mell, Charles S. Coffey, James D. Murphy   +6 more
semanticscholar   +1 more source

A Multifunctional Nanodelivery System Modified by Fusion Peptides Acts as Teriparatide Carrier for Noise‐Induced Hearing Loss Therapy

Advanced Science, EarlyView.
The fusion peptide LR27‐modified thermosensitive nanodelivery system exhibits both hair cell targeting and inner ear penetrating properties. This system sustainably and effectively delivers PTH1‐34 to the inner ear of a hearing loss mouse model via the synergistic effects of multiple peptides, achieving satisfactory hearing protection through ...
Jiawen Li, Zhuowen Hao, Fangzi Ke, Zhihui Liu, Weilong Wang, Sihui Wen, Fan Wu, Bowen Xu, Miao He, Shengyu Zou, Xiong Chen, Jingfeng Li, Zuhong He   +12 more
wiley   +1 more source

The Role of Bilateral Versus Ipsilateral Neck Dissection in Oropharyngeal and Oral Cancer with Contralateral cN0 Neck in cT3 and cT4 Disease

Journal of Medical Sciences and Health
Introduction: Head and neck cancer (HNC) is a significant global health issue, with Head and Neck Squamous Cell Carcinoma (HNSCC) ranking among the most prevalent cancers worldwide.
Bhut Vishal, Vinod Kumar Dhakad
doaj   +1 more source

Gastric pseudoaneurysm in the setting of Loey’s Dietz Syndrome [PDF]

, 2012
Loey’s Dietz syndrome is a disorder of connective tissue caused by a mutation in the genes that encode transforming growth factor (TGF) beta receptor 1 and 2.
Johston, Troy Alan, Likes, Maggie L.
core   +1 more source

Complications of Neck Dissection [PDF]

, 2012
Head & neck cancer is the major problem due to its associated morbidity and mortality. It is the sixth most common cancers and the eighth cause of cancer mortality in the world(1). The most important prognostic factor in the management of head and neck cancer is the presence of cervical lymph node metastasis. Neck dissection has been a well‐established
Soheila Nikakhlagh, Nader Saki
openaire   +3 more sources