Results 41 to 50 of about 2,463,745 (336)
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Case report of a surgical neck humerus fracture due to strength training
Trauma Case Reports, 2019 The incidence of the surgical neck fractures of humerus is increasing, especially among younger age groups as they place higher demands on their shoulder joints.
Ahmed Barakat, N. Cameron Hatrick
doaj +1 more source
Miraculous escape in a case of penetrating neck injury by arrow
Indian Journal of Vascular and Endovascular Surgery, 2021 Penetrating neck injuries due to arrowheads have become extremely rare in most of the nations. Although the basic principles of management remain the same as that of other penetrating injuries, certain extra precautions need to be taken while managing ...
Raja Lahiri, Subhendu Sekhar Mahapatra
doaj +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Analysis of ear, nose and throat injuries reporting to a tertiary care hospital in Sikkim [PDF]
Al Ameen Journal of Medical Sciences, 2017 Aims: This study aims to analyse the pattern of ENT injuries in patient presenting to the institute. Settings and Design: This study was conducted in the department of ENT, Sikkim Manipal Institute of Medical Sciences, Gangtok. Methods and Material: Date
Abhijeet Bhatia, Isha Preet Tuli
doaj
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Ipsilateral Acetabular and Femoral Neck and Shaft Fractures
Case Reports in Orthopedics, 2015 Floating hip injuries and ipsilateral femoral neck and shaft fractures are rare. Additionally, the simultaneous occurrence of these injuries is extremely rare, and only one case report of the simultaneous occurrence of these injuries has been published ...
Hideto Irifune +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan +6 more
wiley +1 more source
Characteristics of Homicidal Cut-Throat Death Cases
Arab Journal of Forensic Sciences & Forensic MedicineCut-throat cases are rare, posing significant challenges for forensic pathologists in determining the manner of death. This study aims to identify key findings that can assist in determining the origin of homicidal intent based on crime scene ...
Hasan A. Abder-Rahman +7 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Facioscapulohumeral muscular dystrophy type 1 (FSHD1) is a progressive neuromuscular disorder with no approved treatments. Identifying reliable biomarkers is critical to monitor disease severity, activity, and progression. Interleukin‐6 (IL‐6) has been proposed as a candidate biomarker, but longitudinal validation is limited ...
Jonathan Pini +13 more
wiley +1 more source