Results 41 to 50 of about 98,204 (296)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A national survey of clinical practice for the management of whiplash-associated disorders in UK emergency departments [PDF]

, 2009
Objective: To undertake a national survey to determine current practice for the management of whiplash injuries in UK emergency departments (ED). Methods: Postal questionnaire survey.
Cooke, M, Lamb, S. E. (Sallie E.), Underwood, M., Perry, Joanna, Cooke, Matthew (Professor of clinical systems design), Gates, S, Williams, M.A., Underwood, Martin, Lamb, S.E., Underwood, M, Withers, E., Perry, J, Cooke, Matthew W, Cooke, M., Withers, Emma J., Williams, Mark, Williamson, E, Williams, MA, Gates, Simon, Lamb, Sarah, Williams, M A, Gates, S., Lamb, S E, Williams, Mark A., Withers, E, Williamson, E., Williamson, Esther M., Lamb, SE   +27 more
core   +1 more source

Rupture of the internal jugular vein and tension pneumothorax in a penetrating neck-lung injury due to iron splinters: a case report

Medisains
Background: Penetrating neck injuries are relatively rare but pose significant challenges due to the concentration of vital structures in this area. This case report presents a unique in-stance of a 20-year-old male with a penetrating neck injury caused ...
Brilliant Brilliant, Muhammad Sabri, Annisa Tria Fadilla, Hariadi Hatta   +3 more
doaj   +1 more source

Delayed Presentation of an Unusual Transpharyngeal Penetrating Neck Injury by a Wooden stick: A Case Report [PDF]

Malaysian Orthopaedic Journal, 2010
Penetrating neck trauma is a horrifying injury. Patients may present with sudden death, or life threatening injuries such as catastrophic haemorrhage, major vessel injury, injuries to the respiratory or digestive tract, neurological deficits, or bony ...
S Grover, M Chaudhry
doaj  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Autopsy Findings in Hanging: A 10-Year Prospective Study of 660 Cases

Forensic Sciences
Background/Objectives: Hanging is the most common method of suicide in most countries worldwide. It is characterized by high lethality, technical simplicity, and typical autopsy findings.
Roman Kuruc, Andrea Szórádová, Jozef Šidlo, Michaela Neszméry, Ľuboš Nižnanský   +4 more
doaj   +1 more source

Case report of a surgical neck humerus fracture due to strength training

Trauma Case Reports, 2019
The incidence of the surgical neck fractures of humerus is increasing, especially among younger age groups as they place higher demands on their shoulder joints.
Ahmed Barakat, N. Cameron Hatrick
doaj   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Does inter-vertebral range of motion increase after spinal manipulation? A prospective cohort study. [PDF]

, 2014
Background: Spinal manipulation for nonspecific neck pain is thought to work in part by improving inter-vertebral range of motion (IV-RoM), but it is difficult to measure this or determine whether it is related to clinical outcomes.
Alan C Breen, Branney, Jonny, Branney, Jonathan, Jonathan Branney, Breen, Alan C., Breen, Alan   +5 more
core   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source