Results 61 to 70 of about 2,844,189 (288)

The Lupus Damage Index Revision Program: Results From the Item Generation and Reduction Phases

Arthritis Care &Research, EarlyView.
Objective A data‐driven and expert/patient consensus‐based project to develop a revised Systemic Lupus International Collaborating Clinics (SLICC)/American College of Rheumatology (ACR) Damage Index (SDI) is under way supported by SLICC, ACR, and the Lupus Foundation of America. Our objective is to report the item generation and reduction phase results
Burak Kundakci, Megan R. W. Barber, Ann E. Clarke, Sindhu R. Johnson, Anselm Mak, Hermine I. Brunner, Murat Inanc, Rosalind Ramsey‐Goldman, Guillermo Ruiz‐Irastorza, Ellen M. Ginzler, John G. Hanly, Alexandra Legge, Cynthia Aranow, Laurent Arnaud, Nathalie Costedoat‐Chalumeau, Dafna D. Gladman, Søren Jacobsen, Michelle Petri, Clovis A. Silva, Évelyne Vinet, Alexandre E. Voskuyl, SDI Revision Literature Review Groups, SDI Revision Delphi Panel, SDI Revision Item Reduction Committee, SDI Revision Clinical Domain Groups, Ian N. Bruce   +25 more
wiley   +1 more source

Neck pain and disability: A cross-sectional survey of the demographic and clinical characteristics of neck pain seen in a rheumatology clinic [PDF]

, 2004
This hospital-based cross-sectional cohort study examines the clinical and demographic features of neck pain, disability (using the Northwick Park neck pain questionnaire) and relationships to handicap in employment.
C.A. Frank, Frank, AO, Frank, CA, L.H. De Souza, A.O. Frank, De Souza, LH   +5 more
core   +1 more source

African Head and Neck Society Clinical Practice guidelines for thyroid nodules and cancer in developing countries and limited resource settings [PDF]

, 2020
Background: International thyroid nodule and cancer management guidelines generally fail to take into account potential limitations in diagnostic and treatment resources.
Justin Yu, Mpessa E. Maurice, Mashamba, Victor, Merry Sebelik, Aswani, Joyce, Cairncross, Lydia, Bogale, Mesele, Patrick Noah, Innocent Kundiona, Kenneth Baidoo, Michael G. Moore, Chege Macharia, Otiti, Jeffrey, Evelyne Diom, Susan Cordes, Koné, Fatogoma I., Jeffrey Otiti, Macharia, Chege, Lydia Cairncross, Arnaud Itiere, Khaled Twier, Koch, Wayne, Itiere, Arnaud, Mark Zafereo, Sebelik, Merry, Mohammed, Garba M., Omutsani, Mary, Fatogoma I. Koné, Mary Omutsani, Anna Konney, Paul A. Onakoya, Johannes J. Fagan, Maurice, Mpessa E., Randolph, Gregory W., Cordes, Susan, Mugabo, Rajab M., Diom, Evelyne, Moore, Michael G., Noah, Patrick, Victor Mashamba, Melesse G. Biadgelign, Daniel, Adekunle, Yu, Justin, Biadgelign, Melesse G., Lisa A. Orloff, Gregory W. Randolph, Fagan, Johannes J., Rajab M. Mugabo, Garba M. Mohammed, Mesele Bogale, Baidoo, Kenneth, Joyce Aswani, Konney, Anna, Adekunle Daniel, Kundiona, Innocent, Onakoya, Paul A., Zafereo, Mark, Todsen, Tobias, Tobias Todsen, Orloff, Lisa A., Wayne Koch, Twier, Khaled   +61 more
core   +1 more source

Myogenic Fusogen‐Engineered Lipid Nanoparticles Enhance mRNA Delivery in Skeletal Muscle

Advanced Functional Materials, EarlyView.
This study reports a biomimetic strategy of engineering full‐length Myomaker, a muscle‐specific fusogen, into lipid nanoparticles (LNPs) to harness the native myoblast fusion capability for skeletal muscle mRNA delivery. The resulting Mymk‐LNPs enhance transfection in differentiating myocytes and enable Cre‐mediated reporter activation in injured ...
Fangyu Zhang, Zhisheng Xu, Yaou Duan, Yehui Sun, Shiying Wu, Tao Long, Mateusz Durbacz, Li Zhang, Yufen Xiao, Yu‐Chung Pien, Erick D. Guerrero, Zeru Tian, Xu Wang, Pratima Basak, Sumanta Chatterjee, Ning Liu, Xiaochun Li, Eric N. Olson, Daniel J. Siegwart   +18 more
wiley   +1 more source

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

Advanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu, Lorenzo Moroni, Nicolas Lebonvallet, Vincent Flacher, Paul Wieringa   +4 more
wiley   +1 more source

Magnetically Driven Biofabrication for Tissue Engineering: From Nanoparticle Design to Mag‐ATMP Translation

Advanced Healthcare Materials, EarlyView.
Magnetically responsive nanoparticles enable remote control over biomaterials, cells, and engineered tissues. This review summarizes material design, biological safety, fabrication and actuation strategies, computational validation, and translational pathways that support the development of magnetic tissue‐engineering platforms and future magnetically ...
Konstantinos Ioannidis, Dimitrios Lefas, Maya Guilliams, Jackie Van Grootenbril, Isaak Decoene, Dimitrios Sakellariou, Bart Smeets, Stefanos Mourdikoudis, Ioannis Papantoniou   +8 more
wiley   +1 more source

PLL‐g‐HPA Hydrogel Microneedles Loaded With Rhoifolin Target Macrophages to Alleviate Fibroblast Senescence for Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Diabetic wound healing is hindered by a pathological crosstalk wherein elevated IL‐11 induces M1 macrophage polarization, leading to IL‐1β/IL‐6 release and subsequent fibroblast senescence via RAS/p38MAPK/p53/E2F1 signaling. Here, we develop a Gel@M‐Rho microneedle patch that delivers rhoifolin‐loaded, macrophage membrane‐coated nanoparticles to target
Jiewen Liao, Lin Gan, Li Lu, Lizhi Ouyang, Yuan Xiong, Fawwaz Al‐Smadi, Guandong Dai, Mohammad‐Ali Shahbazi, Bobin Mi, Mengfei Liu, Guohui Liu   +10 more
wiley   +1 more source

Advanced head and neck surgery training during the COVID-19 pandemic. [PDF]

, 2020
BackgroundThe COVID‐19 pandemic has significantly impacted medical training. Here we assess its effect on head and neck surgical education.MethodsSurveys were sent to current accredited program directors and trainees to assess the impact of COVID‐19 on ...
Donald T. Weed, Marc A. Cohen, Punam Thakkar, Bewley, Arnaud F, Kang, Steven, Andrew Shuman, Weed, Donald T, Moore, Michael G, Weed, Donald T., Maisie Shindo, Coffey, Charles S, Moore, Michael G., Michael G. Moore, Amy C. Hessel, Jalisi, Scharukh, Newman, Jason G, Liana Puscas, Shindo, Maisie, Thakkar, Punam, Babak Givi, Hessel, Amy C, Scharukh Jalisi, Hessel, Amy C., Arnaud F. Bewley, Shuman, Andrew, Jason G. Newman, Ara Chalian, Bewley, Arnaud F., Coffey, Charles S., Givi, Babak, Puscas, Liana, Chalian, Ara, Cohen, Marc A, Charles S. Coffey, Newman, Jason G., Steven Kang, Cohen, Marc A.   +36 more
core   +1 more source

Upscaling the Fabrication of Rod‐Shaped Microgels: A Microfluidic Method Combining Step‐Emulsification With Consecutive Droplet Confinement in Parallelized Microchannels

Advanced Materials, EarlyView.
A microfluidic method is presented which enables parallelized fabrication of rod‐shaped microgels, based on step‐emulsification (SE) droplet generation and subsequent droplet distribution and confinement, combined in a single device. Microgel rods are fabricated in parallel at different flow rates based on two light‐mediated crosslinking chemistries ...
Matthias Mork, Ninon Möhl, Greta Romahn, Laura Klasen, Cédric Bergerbit, Laura De Laporte   +5 more
wiley   +1 more source

Effect of vibration exposure duration on discomfort [PDF]

, 2008
The comfort of a seated person exposed to vibration is known to depend on the magnitude, frequency content, and direction of the excitation. A review of the literature showed that very little is known about the effects of the duration of exposure to ...
Gallais, Cedric
core   +1 more source