Results 61 to 70 of about 55,005 (210)
Differential expression of TKS4 isoforms and their role in cellular processes in breast cancer
TKS4 isoforms are differentially expressed across human cell lines. TKS4L interacts with six novel SRC homology 3‐containing proteins, whereas no interactions were detected for TKS4b. SRC‐mediated phosphorylation promotes interactions of TKS4 with SH2 domains.
Serhii Kropyvko +10 more
wiley +1 more source
ABSTRACT Introduction Artificial intelligence (AI) is a branch of technology enabling machines to emulate complex human skills; it can also entail problem‐solving using bioinspired methods. It is used for automating systematic literature reviews (SLR), that is, defining a clinical question, locating relevant literature, preliminary screening, study ...
Ana M. Barragán +5 more
wiley +1 more source
Abstract Background Trigeminal‐mediated headshaking (TMHS) in horses shares clinical features with human trigeminal neuralgia (HTN). Increased levels of the neuropeptide calcitonin gene‐related peptide (CGRP) have been found in the blood and cerebrospinal fluid (CSF) of HTN patients. Inhibition of CGRP in humans has shown promise for pain relief.
Lisa Annabel Weber +7 more
wiley +1 more source
Cinnamaldehyde derived from Cinnamomum species exerts multitarget anticancer effects by promoting oxidative stress, mitochondrial dysfunction, apoptosis, cell‐cycle arrest, autophagy, and epigenetic changes, and by suppressing mitogen‐activated protein kinase (MAPK), phosphoinositide 3‐kinase/protein kinase B/mechanistic target of rapamycin (PI3K/Akt ...
Gervason Moriasi +6 more
wiley +1 more source
Cardiovascular disease incidence and cancer risk in two large European prospective cohorts
What's new? Cardiovascular disease (CVD) and cancer share risk factors and biological mechanisms, raising questions about potential associations between the two, particularly regarding CVD duration and cancer onset. Whether CVD influences subsequent cancer risk, however, remains inconclusive.
Emma Fontvieille +25 more
wiley +1 more source
Urethral injury during vaginal delivery: Incidence, management and long‐term outcomes
Abstract Objective This study examines the incidence, obstetric risk factors, surgical management, and long‐term outcomes of obstetric‐associated urethral injuries during vaginal deliveries. Methods A retrospective case series was conducted at a single, tertiary university‐affiliated medical center between January 2018 and December 2023.
Yoav Baruch +5 more
wiley +1 more source
De‐escalating radical surgery for select FIGO Stage I cervical cancer
Abstract Four recent prospective trials demonstrated that de‐escalation of radical surgery for select patients with apparent low‐risk, FIGO Stage I cervical cancer does not compromise cancer‐related survival but does improve quality of life and provide the opportunity to preserve fertility.
Sara Moufarrij +5 more
wiley +1 more source
Follicular Lymphoma Arising in an Ileal Neobladder Presenting as a Large Pelvic Mass
ABSTRACT Introduction Secondary malignancies arising in intestinal segments used for urinary diversion are rare, and reports of malignant lymphoma are extremely limited. We report a rare case of follicular lymphoma arising in an ileal neobladder 20 years after radical cystectomy.
Ken Fujita +9 more
wiley +1 more source
ABSTRACT Introduction Squamous cell carcinoma is a rare bladder cancer subtype with poor prognosis in advanced stages. Currently, there is no established systemic therapy, including immune checkpoint inhibitors, for this subtype. Case Presentation A 49‐year‐old man with pure bladder squamous cell carcinoma arising from a diverticulum with pelvic lymph ...
Kazuma Soya +7 more
wiley +1 more source
ABSTRACT Background Despite its clinical importance in primary care, the prevalence and levels of multimorbidity among patients receiving home‐based medical care remain poorly characterized, and its potential impact on emergency home visits is unclear.
Gen Nakayama +9 more
wiley +1 more source

