Results 31 to 40 of about 283,665 (263)

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Curcumin inhibits chondrocyte apoptosis and inflammation in osteoarthritis via the miR-338-3p/EIF4A1 signaling axis

Hereditas
Objective Osteoarthritis (OA) is a degenerative joint disorder mainly characterized by articular cartilage degradation. Curcumin, the primary bioactive compound derived from turmeric, exhibits anti-inflammatory, antioxidant, and anti-catabolic activities.
Na Dai, Bin Shi
doaj   +1 more source

An injectable curcumin-loaded hydrogel for neuroprotective treatment promote nerve tissue repair in rat severe spinal cord injury

Frontiers in Bioengineering and Biotechnology
IntroductionSpinal Cord Injury (SCI) leads to severe motor and sensory impairments and underscores the urgent need for the development of effective treatment approaches.
Zhaoqing Zhang, Haiyan Ma, Ruisong Tian, Guangwei Li, Fuchang Zhao, Liangyu Xie, Liangyu Xie, Hao Chen   +7 more
doaj   +1 more source

Comparison of forward head in persons with chronic neck pain and healthy persons

مجله پژوهش در علوم توانبخشی, 2011
Introduction: Chronic neck pain is one of the most common problems among computer users. It seems that pain in neck affects the angle of forward head in these people. The aim of this research was to compare the degree of forward head in official computer
Hossein Taheri, Reza Mahdavinejad, Sajjad Bagherian Dehkordi, Zeinab Omidali   +3 more
doaj   +1 more source

Successful treatment of unilateral neck pain with transforaminal epidural steroid injection on the left C3 nerve root: a case report

Journal of International Medical Research, 2020
In clinical practice, neck pain is one of the most common complaints. Although most of the cervical radicular pain is manifested in the neck and upper extremities, C3 or C4 radicular pain only results in neck pain.
Min Cheol Chang, Mathieu Boudier-Revéret, Ming-Yen Hsiao, Shaw-Gang Shyu   +3 more
doaj   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Neck Pain with Fever [PDF]

Journal of the Royal Society of Medicine, 1999
Syrinx was an Arcadian virgin who, when pursued by Pan, turned into a reed, from which Pan made his pipes. She gave her name to the tubular cavitation of the spinal cord. Post-traumatic syrinx is well described in patients with delayed neurological deterioration after spinal cord injury3'4. The period from injury to onset of symptoms is up to 33 years3.
A R, Saha, A M, Blackburn
openaire   +2 more sources

Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji, Jianlong Zhang, Yiming Shi, Shiyu Shan, Yang Du, Guangshuo Li, Ying Jin, Yani Zhang, Chuanying Wang, Yijun Lin, Yuhao Guo, Decai Tian, Xingquan Zhao, Tian Song   +13 more
wiley   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source

Effectiveness of Manipulative Therapy on Neck Pain, Function and Disability. A Systematic Review

Reabilitacijos Mokslai: Slauga, Kineziterapija, Ergoterapija, 2023
Background: Neck pain is a common musculoskeletal issue affecting people worldwide, and manipulative therapy is implemented as a treatment for it.
Nan Xu , Elif Nur Surucu
doaj   +1 more source