Results 51 to 60 of about 3,045,835 (343)

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Is traumatic and non-traumatic neck pain associated with brain alterations? : a systematic review [PDF]

, 2017
Background: Chronic neck pain affects 50% - 85% of people who have experienced an acute episode. This transition and the persistence of chronic complaints are believed to be mediated by brain alterations among different central mechanisms.
Caeyenberghs, Karen, Cagnie, Barbara, Coppieters, Iris, Danneels, Lieven, De Pauw, Robby, Meeus, Mira   +5 more
core  

Self-medication with over-the-counter analgesics : a survey of patient characteristics and concerns about pain medication [PDF]

, 2019
Pain is a common reason for self-medication with over-the-counter (OTC) analgesics. However, this self-treating population has remained largely uncharacterized.
Adriaens, Els, Boussery, Koen, Christiaens, Thierry, Crombez, Geert, Demarche, Sophie, Mehuys, Els, Paemeleire, Koen, Remon, Jean Paul, Van Bortel, Lucas, Van Hees, Thierry, Van Tongelen, Inge   +10 more
core   +2 more sources

Neck Muscle Stiffness Measured With Shear Wave Elastography in Women With Chronic Non-Specific Neck Pain.

Journal of Orthopaedic and Sports Physical Therapy, 2020
STUDY DESIGN Cross-sectional observational study. BACKGROUND Patients with chronic neck pain often perceive increased stiffness of their neck muscles; yet there is uncertainty as to whether people with neck pain present with evidence of an objective ...
A. Dieterich, U. Yavuz, F. Petzke, A. Nordez, D. Falla   +4 more
semanticscholar   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Immediate Effects of Cervical Spine Thrust Joint Manipulation on Gait Parameters in Individuals with Neck Pain

, 2018
Purpose/Hypotheses: 1. To investigate for any change in gait parameters in individuals with neck pain while walking with different functional neck conditions immediately following cervical thrust joint manipulation (TJM) versus a sham intervention. 2. To
Albano, Marc Anthony D., Blok, Emily, Gronert, Beau, Masuda, Ryan   +3 more
core   +1 more source

Prevalence of neck pain in subjects with metabolic syndrome - a cross-sectional population-based study [PDF]

, 2010
Background Metabolic syndrome (MetS) is increasingly common. Obesity has been suggested to associate with neck pain but prevalence of neck pain in subjects with MetS has not been studied.
Pekka Mäntyselkä, Hannu Kautiainen, Mauno Vanhala   +2 more
core   +2 more sources

Manipulation and Mobilization for Treating Chronic Nonspecific Neck Pain: A Systematic Review and Meta-Analysis for an Appropriateness Panel.

Pain Physician, 2019
BACKGROUND Mobilization and manipulation therapies are widely used by patients with chronic nonspecific neck pain; however, questions remain around efficacy, dosing, and safety, as well as how these approaches compare to other therapies.
I. Coulter, C. Crawford, H. Vernon, E. Hurwitz, R. Khorsan, M. Booth, P. Herman   +6 more
semanticscholar   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source