Results 11 to 20 of about 1,041,101 (262)

The Encapsulation of Febuxostat into Emulsomes Strongly Enhances the Cytotoxic Potential of the Drug on HCT 116 Colon Cancer Cells

open access: yesPharmaceutics, 2020
Febuxostat (FBX) is a drug able to inhibit xanthine oxidase and reduce uric acid production commonly used for the treatment of hyperuricemia in subjects suffering from gout.
Usama A. Fahmy   +7 more
doaj   +1 more source

Molecular identification of lactic acid bacteria SR6 strain and evaluation of its activity as an anticancer in T47D cell line [PDF]

open access: yesVeterinary World, 2022
Background and Aim: Breast cancer is the most common type of cancer in women because it attacks the productive age. Preliminary studies showed that lactic acid bacteria (LAB) strain SR6 from the Bali cattle colon has the potential to act as a superior ...
Ida Bagus Ngurah Swacita   +3 more
doaj   +1 more source

Safety Evaluation of Nanotechnology Products

open access: yesPharmaceutics, 2021
Nanomaterials are now being used in a wide variety of biomedical applications. Medical and health-related issues, however, have raised major concerns, in view of the potential risks of these materials against tissue, cells, and/or organs and these are ...
Abraham J. Domb   +3 more
doaj   +1 more source

Targeting claudin‐overexpressing thyroid and lung cancer by modified Clostridium perfringens enterotoxin

open access: yesMolecular Oncology, 2020
Clostridium perfringens enterotoxin (CPE) can be used to eliminate carcinoma cells that overexpress on their cell surface CPE receptors – a subset of claudins (e.g., Cldn3 and Cldn4).
Anna Piontek   +10 more
doaj   +1 more source

A Case of Ewing’s Sarcoma of the Jejunum: A Radiological Perspective on Challenges in Diagnosis [PDF]

open access: yesJournal of Clinical and Diagnostic Research
Ewing’s Sarcoma (ES) of the jejunum is an exceptionally rare malignancy. It belongs to the family of small round blue cell tumours and primarily affects children and young adults, with gastrointestinal involvement being highly uncommon, particularly in ...
Tushar Kalekar   +3 more
doaj   +1 more source

Invasive Mycotic Infection in Orofacial Region

open access: yesČeská Stomatologie a Praktické Zubní Lékařství, 2010
The authors describe the occurrence of zygomycosis in orofacial region in two patients with hematological malignancy.Invasive mycotic infections represent serious complications in the therapy of oncological patients.
Z. Daněk   +2 more
doaj   +1 more source

Programmed cell death and liver diseases

open access: yesВестник трансплантологии и искусственных органов, 2022
Cell death represents the most critical pathologic entity in liver disease, which dictates pathologic consequences such as inflammation, fibrosis, and cell transformation.
N. A. Onishchenko   +4 more
doaj   +1 more source

Surviving the perilous: A case report on an urgent approach to necrotizing fasciitis

open access: yesClinical Case Reports, 2023
Key Clinical Message Necrotizing fasciitis is a rare, fatal, and rapidly progressing bacterial infection of fascia and subcutaneous tissues. Skin necrosis, pain, bullae, and erythema are the common manifestations. Early diagnosis and prompt treatment can
Bishal Kunwor   +4 more
doaj   +1 more source

Evaluation of acute toxicity of genabilic acid (menbutone 10%) in rabbits

open access: yesWorld Rabbit Science, 2014
A complete investigation of the acute toxicity of a choleretic compound, menbutone, was performed in rabbits, including lethal dose for 50% of rabbits determination, clinical signs observation and in vivo and post-mortem examinations.
S. O. El Okle, G. H. Tohamy, A. M. Lebda
doaj   +1 more source

Non-canonical functions of regulated cell death machinery regulate cellular growth, invasion and the interplay between cell death modalities

open access: yesFrontiers in Cell Death
The exploration of multiple regulated cell death (RCD) pathways and the recognition that several cell death-related proteins, including caspases, serve non-canonical roles have significantly expanded and diversified cell death research. Caspases not only
Y. Shan, Y. Shan, B. Mollereau
doaj   +1 more source

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