Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death. [PDF]
Apoptosis is a genetically regulated cell suicide programme mediated by activation of the effector caspases 3, 6 and 7. If apoptotic cells are not scavenged, they progress to a lytic and inflammatory phase called secondary necrosis.
Alnemri, Diana +5 more
core +2 more sources
Photodynamic therapy of prostate cancer by means of 5-aminolevulinic acid-induced protoporphyrin IX - In vivo experiments on the dunning rat tumor model [PDF]
Objective: In order to expand the use of photodynamic therapy (PDT) in the treatment of prostate carcinoma (PCA), the aim of this study was to evaluate PDT by means of 5-aminolevulinic acid (5-ALA)-induced protoporphyrin IX ( PPIX) in an in vivo tumor ...
Baumgartner, Reinhold +12 more
core +1 more source
Clostridium perfringens enterotoxin (CPE) can be used to eliminate carcinoma cells that overexpress on their cell surface CPE receptors – a subset of claudins (e.g., Cldn3 and Cldn4).
Anna Piontek +10 more
doaj +1 more source
Improved Visualization of the Necrotic Zone after Microwave Ablation Using Computed Tomography Volume Perfusion in an In Vivo Porcine Model [PDF]
After hepatic microwave ablation, the differentiation between fully necrotic and persistent vital tissue through contrast enhanced CT remains a clinical challenge.
Bressem, Keno K. +8 more
core +1 more source
A Case of Ewing’s Sarcoma of the Jejunum: A Radiological Perspective on Challenges in Diagnosis [PDF]
Ewing’s Sarcoma (ES) of the jejunum is an exceptionally rare malignancy. It belongs to the family of small round blue cell tumours and primarily affects children and young adults, with gastrointestinal involvement being highly uncommon, particularly in ...
Tushar Kalekar +3 more
doaj +1 more source
Rethinking the role of alpha toxin in Clostridium perfringens-associated enteric diseases : a review on bovine necro-haemorrhagic enteritis [PDF]
Bovine necro-haemorrhagic enteritis is an economically important disease caused by Clostridium perfringens type A strains. The disease mainly affects calves under intensive rearing conditions and is characterized by sudden death associated with small ...
Deprez, Piet +6 more
core +3 more sources
Invasive Mycotic Infection in Orofacial Region
The authors describe the occurrence of zygomycosis in orofacial region in two patients with hematological malignancy.Invasive mycotic infections represent serious complications in the therapy of oncological patients.
Z. Daněk +2 more
doaj +1 more source
Enhancement of experimental metastasis by tumor necrosis factor [PDF]
The influence of endogenous and exogenous tumor necrosis factor (TNF) on metastasis was investigated in an experimental fibrosarcoma metastasis model.
Echtenacher, Bernd +5 more
core +2 more sources
Programmed cell death and liver diseases
Cell death represents the most critical pathologic entity in liver disease, which dictates pathologic consequences such as inflammation, fibrosis, and cell transformation.
N. A. Onishchenko +4 more
doaj +1 more source
Placental-mediated increased cytokine response to lipopolysaccharides: a potential mechanism for enhanced inflammation susceptibility of the preterm fetus. [PDF]
BackgroundCerebral palsy is a nonprogressive motor impairment syndrome that has no effective cure. The etiology of most cases of cerebral palsy remains unknown; however, recent epidemiologic data have demonstrated an association between fetal neurologic ...
Belkacemi, Louiza +4 more
core +1 more source

