Results 51 to 60 of about 5,052,099 (298)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

The pathogenesis of infectious necrotic hepatitis (black disease) of sheep

open access: yes, 1970
The literature relating to infectious necrotic hepatitis is critically reviewed and discussed. The bacteriological, parasitological and other techniques used in this study are outlined.
Bagadi, Hammad Omer
core   +3 more sources

Necrotic Enteritis in Broiler Chickens: Studies in Disease Reproduction and Pathogenesis

open access: yes, 2007
Necrotic enteritis in poultry is caused by Clostridium perfringens type A, and is estimated to cost the worldwide poultry industry approximately $2 billion dollars a year, due to increased mortality and decreased feed conversion and weight gain.
Cooper, Kerry Kevin
core   +5 more sources

Necrotizing Fasciitis of the Breast Underlying an Autoimmune Disease

open access: yesEuropean Journal of Case Reports in Internal Medicine, 2021
Necrotizing fasciitis is a serious soft tissue infection that causes necrosis of the subcutaneous tissues and the muscle fascia. It is associated with a high mortality rate of around 25%. Necrotizing fasciitis of the breast is a rare entity. It is a rapidly progressive life-threatening condition which can lead to sepsis with multiple organ failure.
Yousfi, Jaouad   +3 more
openaire   +4 more sources

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Role of Wheat Based Diet on the Pathology of Necrotic Enteritis in Turkeys

open access: yesScientifica, 2016
The study was conducted to investigate the effects of wheat based diet on the pathology of necrotic enteritis in turkeys. Turkeys were divided into four groups. Groups A and B were kept as noninoculated and fed normal commercial diet while groups C and D
Sajid Umar   +7 more
doaj   +1 more source

Methods of complex evaluation of the necrotic disease of beech

open access: yesJournal of Forest Science, 2007
The authors elaborated a new complex methodical approach to the evaluation of necrotic disease of beeches. They used two evaluation scales: a scale for the evaluation of stems and a scale for the evaluation of beech crowns.
A. Cicák   +3 more
doaj   +1 more source

Detection of beet soil-borne virus and beet virus Q in sugarbeet in Greece [PDF]

open access: yes, 2010
Sugar beet plants with typical rhizomania symptoms were collected from the five major cultivation zones of Greece. The presence of Beet necrotic yellow vein virus (BNYVV), the primary causal agent of the disease, was ascertained by DAS-ELISA in 38 out of
Prins, M., Pavli, R., Skaracis, G.N.
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

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