Results 41 to 50 of about 57,553 (263)
Necrotizing enterocolitis (NEC) is the most common severe neonatal gastrointestinal emergency that predominantly affects premature infants. Its morbidity and mortality is similar to other severe childhood diseases such as meningitis and leukemia, and is becoming increasingly recognized as a major cause of neurodevelopmental delays.
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Advances in necrotizing enterocolitis [PDF]
To evaluate recently reported findings on necrotizing enterocolitis, Paying particular attention to pathogenesis, management and preventative strategies.The articles covered in this report consist of randomized and quasi-randomized trials, case control studies, meta-analyses and reviews published recently.
Nelson Diniz, de Oliveira +1 more
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Preterm gut microbiota and metabolome following discharge from intensive care [PDF]
The development of the preterm gut microbiome is important for immediate and longer-term health following birth. We aimed to determine if modifications to the preterm gut on the neonatal intensive care unit (NICU) impacted the gut microbiota and ...
Skeath, Tom +12 more
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AimThe aim of this study was to evaluate long-term behavioural and neurodevelopmental complications of neonatal necrotizing enterocolitis at school age.MethodThis was a historic cohort study comparing all surviving children born in Denmark between 1st of
Mathias Lühr Hansen +4 more
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Spastic paraplegia 61 is a rare, complicated form of hereditary spastic paraplegia characterized by diffuse sensory and motor polyneuropathy. Knowledge about the clinical manifestations of disease in patients with this genetic condition is limited.
E.K. Ninmer +3 more
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Introduction Portal venous gas (PVG) is common in necrotizing enterocolitis and occasionally occurs in neonates after umbilical vein catheterization (UVC). Therefore, determining the cause of PVG requires further clinical evaluation in these cases.
Jun Wang +4 more
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Probiotics and necrotizing enterocolitis [PDF]
In this review, we summarize existing knowledge regarding the effects of probiotics on necrotizing enterocolitis (NEC). We review the role of the microbiome in NEC and pre-clinical data on mechanisms of probiotic action. Next, we summarize existing randomized controlled trials and observational studies of probiotics to prevent NEC.
Ravi Mangal, Patel, Mark A, Underwood
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BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
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Probiotics and necrotizing enterocolitis [PDF]
Probiotics for the prevention of necrotizing enterocolitis have attracted a huge interest. Combined data from heterogeneous randomised controlled trials suggest that probiotics may decrease the incidence of NEC. However, the individual studies use a variety of probiotic products, and the group at greatest risk of NEC, i.e., those with a birth weight of
Hall, Nigel, Eaton, Simon, Fleming, Paul
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Preclinical model of neonatal necrotizing enterocolitis
The disclosure provides methods of generating a murine model of neonatal necrotizing enterocolitis, whereby the generated murine animal exhibits at least one symptom of neonatal necrotizing enterocolitis.
Maheshwari, Akhil, Krishnan, Mohan Kumar
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