Results 81 to 90 of about 16,951 (222)

Contrast-enhanced computed tomography in acute pancreatitis: does contrast medium worsen its course due to impaired microcirculation? [PDF]

open access: yes, 2018
Background: An early and accurate diagnosis of severe acute (necrotizing) pancreatitis is important to allow timely institution of therapy to limit the extra-pancreatic sequelae of this necrotizing process and to minimize the incidence of super-infection
Anderson, Suzanne   +4 more
core  

Microbiota, Oral Microbiome, and Pancreatic Cancer [PDF]

open access: yes, 2014
Only 30% of patients diagnosed with pancreatic cancer survive one year post-diagnosis. Progress in understanding the causes of pancreatic cancer has been made, including solidifying the associations with obesity and diabetes, and a proportion of cases ...
Izard, Jacques, Michaud, Dominique S.
core   +2 more sources

Primary Streptococcal Peritonitis in a Postpartum Patient: A Rare but Life‐Threatening Condition

open access: yesClinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT We present the case of a 43‐year‐old postpartum woman who developed primary streptococcal peritonitis with a fulminant septic course requiring intensive care. Initial symptoms were nonspecific and improved temporarily, but the patient returned the next day with recurrent pain and markedly elevated inflammatory markers.
Matthias Pimiskern, Helmut Trimmel
wiley   +1 more source

Delayed surgical therapy reduces mortality in patients with acute necrotizing pancreatitis [PDF]

open access: yes, 2011
Objective: To review the trends in management and analyze the factors influencing outcomes of acute necrotizing pancreatitis.Methods: It wa a retrospective analytical study. All adult patients with computed tomography with proven necrotizing pancreatitis
Alvi, Abdul Rehman   +2 more
core   +1 more source

Pathophysiology of acute experimental pancreatitis: Lessons from genetically engineered animal models and new molecular approaches [PDF]

open access: yes, 2005
The incidence of acute pancreatitis is growing and worldwide population-based studies report a doubling or tripling since the 1970s. 25% of acute pancreatitis are severe and associated with histological changes of necrotizing pancreatitis. There is still
Anne Barbara Tietz   +38 more
core   +1 more source

Integrative Genomics Reveals Causal Pleiotropy and Therapeutic Opportunities at the Interface of Acute Pancreatitis and Infection

open access: yesJournal of Hepato-Biliary-Pancreatic Sciences, Volume 33, Issue 3, Page 194-207, March 2026.
ABSTRACT Background Understanding the genetic links between acute pancreatitis (AP) and its infectious comorbidities is crucial for prognosis and therapy, yet remains underexplored. Methods We conducted a comprehensive post‐GWAS analysis using large‐scale summary statistics for AP and 16 infectious diseases. To pinpoint pleiotropic genes, we integrated
Bo Zou   +6 more
wiley   +1 more source

Зміни клінічних підходів та лікувальної тактики при гострому панкреатиті у світлі переглянутої класифікації Атланта 2012 [PDF]

open access: yes, 2017
Гострий панкреатит (ГП) та його ускладнення є актуальною проблемою абдомінальної хірургії. Для глибокого й ефективного розуміння цього захворювання важливо знати його актуальну класифікацію та її еволюцію.
Десятерик, В.І.   +1 more
core  

Mitochondrial Dysfunction in Propionic Acidemia: A Case‐Report and Review of the Literature

open access: yesJIMD Reports, Volume 67, Issue 2, March 2026.
ABSTRACT Propionic acidemia is an inborn error of metabolism involving an enzymatic defect of propionyl‐CoA carboxylase that results in the build‐up of toxic metabolites which can induce metabolic decompensation. Secondary mitochondrial dysfunction in propionic acidemia has been commonly recognized; however, its clinical presentation and management are
Brandon K. Walther   +5 more
wiley   +1 more source

Necrotizing Panniculitis as an Uncommon Manifestation of Acute Pancreatitis [PDF]

open access: yes, 2017
Pancreatic panniculitis is a rare disorder affecting 2–3% of patients with pancreatic disease. The findings are characterized by tender, erythematous, subcutaneous nodules which may undergo spontaneous ulceration with discharge of brownish and viscous ...
Amaradio, Maria Domenica   +5 more
core   +3 more sources

Human Cyclophilins—An Emerging Class of Drug Targets

open access: yesMedicinal Research Reviews, Volume 46, Issue 2, Page 475-512, March 2026.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova   +3 more
wiley   +1 more source

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