Results 31 to 40 of about 8,807 (99)
Potential role for nectin-4 in the pathogenesis of pre-eclampsia: a molecular genetic study
BMC Medical Genetics, 2018 Background Nectins are cell adhesion molecules that play a pivotal role in adherens junctions and tight junctions. Our previous study using whole-genome oligonucleotide microarrays revealed that nectin-4 was upregulated in pre-eclamptic placentas.
Mayuko Ito +12 more
doaj +1 more source
Nectin-2 (CD112) Is Expressed on Outgrowth Endothelial Cells and Regulates Cell Proliferation and Angiogenic Function. [PDF]
PLoS ONE, 2016 Outgrowth endothelial cells (OECs) are a subpopulation of endothelial progenitor cells (EPCs) that have the capacity for proliferation and the ability to promote angiogenesis.
YeonSung Son +7 more
doaj +1 more source
Cancer Cell International, 2019 Background Nectin-4, also known as PVRL4 (poliovirus-receptor-like 4), is specifically expressed in the embryo and placenta. Recent studies have reported that the Nectin-4 is over-expressed in multiple human cancers, and such abnormal expression is ...
Haifeng Deng +4 more
doaj +1 more source
The expression of the Nectin complex in human breast cancer and the role of Nectin-3 in the control of tight junctions during metastasis. [PDF]
PLoS ONE, 2013 Nectins are a family of integral protein molecules involved in the formation of functioning Adherens and Tight Junctions (TJ). Aberrant expression is associated with cancer progression but little is known how this effects changes in cell behaviour.
Tracey A Martin +3 more
doaj +1 more source
Nectin-4-targeted immunoSPECT/CT imaging and photothermal therapy of triple-negative breast cancer
Journal of Nanobiotechnology, 2022 Background Triple-negative breast cancer (TNBC) is more prone to distant metastasis and visceral recurrence in comparison to other breast cancer subtypes, and is related to dismal prognosis.
Fuqiang Shao +15 more
doaj +1 more source
Expression of canine distemper virus receptor nectin-4 in the central nervous system of dogs
Scientific Reports, 2017 Canine distemper virus (CDV) exhibits lymphotropic, epitheliotropic, and neurotropic nature, and causes a severe systemic infection in susceptible animals.
Watanyoo Pratakpiriya +7 more
doaj +1 more source
Nectin-4 is a new histological and serological tumor associated marker for breast cancer
BMC Cancer, 2007 Introduction Breast cancer is a complex and heterogeneous disease at the molecular level. Evolution is difficult to predict according to classical histoclinical prognostic factors.
Sauvan Richard +18 more
doaj +1 more source
Brain Sciences, 2022 Purpose: Neuropathic pain often originates from nerve injury or diseases of the somatosensory nervous system. However, its specific pathogenesis remains unclear.
Min Zhu, Hongli Yu, Ying Sun, Wenli Yu
doaj +1 more source
The significance of Survivin and Nectin-4 expression in the prognosis of breast carcinoma
Folia Histochemica et Cytobiologica, 2011 To investigate the prognostic significance of Survivin and Nectin-4 expression in breast carcinomas. Imprint smears were obtained from 140 breast carcinoma specimens and studied immunocytochemically for the expression of Survivin and Nectin-4.
Pauline Athanassiadou +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source