Results 71 to 80 of about 8,807 (99)

Enfortumab vedotin promotes PD-L1 expression in urothelial carcinoma via NF-κB and STAT3 pathways highlighting mechanisms of immune evasion and potential for combination therapy

BMC Immunology
Background PD-1/PD-L1 inhibitors have revolutionized urothelial carcinoma (UC) treatment; however, the effects of prior or concurrent therapies on PD-L1 regulation remain unclear.
Hirohito Naito, Rikiya Taoka, Xia Zhang, Akram Hossain, Yohei Abe, Mikio Sugimoto   +5 more
doaj   +1 more source

Nectin-4-Targeted Radiotheranostics for Personalized Cancer Therapy: A Systematic Review. [PDF]

J Nucl Med
Schäfer L, Altunay B, Morgenroth A, Vogg A, Derks Y, Lammers T, Peña Q, Mottaghy FM, Lütje S.   +8 more
europepmc   +1 more source

Nectin-4 PET for predicting enfortumab vedotin dose-response in urothelial carcinoma. [PDF]

Sci Adv
Mishra A, Sharma AK, Gupta K, Banka DS, Johnson BA, Hoffman-Censits J, Huang P, McConkey DJ, Nimmagadda S.   +8 more
europepmc   +1 more source

Expression of nectin-4 in prostate cancer. [PDF]

North Clin Istanb, 2023
Ordu M, Karaaslan M, Sirin ME, Yilmaz M.
europepmc   +1 more source

Structural basis of nectin-4 recognition by the antibody-drug conjugate 9MW2821. [PDF]

J Biol Chem
Fang P, You M, Wen H, Cao Y, Zhou W, Zhu X, Shi L, Sun X, Li K, Li W, Wang J, Wu H, Tan X.   +12 more
europepmc   +1 more source

Nectin-4 reduces T cell effector function and is a therapeutic target in pancreatic cancer. [PDF]

JCI Insight
Heiduk M, Beer C, Cronjaeger S, Kawaler EA, Sommer U, Baenke F, Digomann D, Bufe LN, Reiche C, Glück J, Hoffmann F, Kim S, Stange DE, Simeone DM, Weitz J, Seifert L, Seifert AM.   +16 more
europepmc   +1 more source

PET Imaging of Nectin-4: A Promising Tool for Personalized/Precision Oncology. [PDF]

Clin Cancer Res, 2023
Jiang D, Lan X, Cai W.
europepmc   +1 more source

Exploring EGFR, Nectin-4, and TROP-2 as Therapeutic Targets for Bladder Cancer Photoimmunotherapy. [PDF]

Molecules
Wolf I, Giess N, Roider C, Schultze-Seemann S, Storz J, Werz DB, Miernik A, Gratzke C, Wolf P.   +8 more
europepmc   +1 more source

Correspondence on "Deficient DNA mismatch repair and Nectin-4 expression in upper tract urothelial carcinoma (UTUC)". [PDF]

J Cancer Res Clin Oncol
Peker P.
europepmc   +1 more source

Scratching the Surface: NECTIN-4 as a Surrogate for Enfortumab Vedotin Resistance. [PDF]

Clin Cancer Res, 2023
Aggen DH, Chu CE, Rosenberg JE.
europepmc   +1 more source