Results 171 to 180 of about 10,275 (197)

Theranostic implications of Nectin-4 oncoprotein in gynecologic cancers: A review

Pathology - Research and Practice
Gynecologic cancers, in order of prevalence, include uterine, ovarian, cervical, vaginal, and vulvar cancers. In 2024, there will be more than 116,000 new cases of gynecologic cancers and 33,800 disease-related deaths. Therefore, a concerted effort has been made to better understand the underlying pathophysiological processes and identify novel ...
Olivia Hooks, Yash Nagpal, Justin T. Childers, Lily T. Childers, Sarfraz Ahmad   +4 more
openaire   +2 more sources

Expression of nectin-4 in canine mammary carcinomas

2019
0285-YL ...
Dolu H., Aydogan A.
openaire   +1 more source

Benefit of nectin-4 targeting with enfortumab vedotin confirmed

Nature Reviews Urology, 2021
openaire   +2 more sources

Abstract 6582: Preclinical characterization of IPH45, a novel topoisomerase I inhibitor ADC targeting Nectin-4 for the treatment of Nectin-4 expressing tumors

Cancer Research
Abstract Background: Nectin-4 is a cell membrane adhesion protein overexpressed in several solid tumors, including urothelial, breast, lung, ovarian, and pancreatic cancers, with limited expression in normal tissues, making it an ideal target for antibody-drug conjugates (ADC).
Romain Remark, Cécile Bonnafous, Laura Chiossone, Caroline Soulas, Cyril Perrier, Guillaume Habif, Sivan Bokobza, Aurélie Maguer, Rachel Courtois, Julie Lopez, Grégory Fenaux, Olivier Benac, Barbara Carrette, Robin Letay-Drouet, Raja Bonifay, Séverine Augier, Léa Simon, Benjamin Rossi, Ariane Morel, Agnès Represa, Nicola Beltraminelli, Yannis Morel, Carine Paturel, Eric Vivier   +23 more
openaire   +1 more source

Nectin cell adhesion molecule-4 (NECTIN-4): A potential target for cancer therapy

European Journal of Pharmacology, 2021
Subhajit Chatterjee, Saptarshi Sinha, Chanakya Nath Kundu   +2 more
exaly  

Loss of NECTIN1 triggers melanoma dissemination upon local IGF1 depletion

Nature Genetics, 2022
Julien Ablain, Harriet T Rothschild, Leonard I Zon   +2 more
exaly  

Nectin-4

2020
openaire   +1 more source

Nectin-2 in general and in the brain

Molecular and Cellular Biochemistry, 2021
Kiyohito Mizutani, Hajime Shiotani, Yoshimi Takai   +2 more
exaly  

Nectin Cell Adhesion Molecule 4 (NECTIN4) Expression in Cutaneous Squamous Cell Carcinoma: A New Therapeutic Target?

Biomedicines, 2021
Yuka Tanaka, Maho Murata, Yoshinao Oda
exaly  

Targeting nectin-4 by antibody-drug conjugates for the treatment of urothelial carcinoma

Expert Opinion on Biological Therapy, 2021
Jeffrey L Wong, Jonathan E Rosenberg
exaly