Results 131 to 140 of about 12,075,699 (303)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Extension of IMS LD for improved pedagogical expressiveness in assessment

open access: yes, 2011
The IMS Learning Design specification (LD) was introduced in order to describe any learning and teaching scenario in a formal way. Its high level of generality, however, may make it difficult for teachers and instructional designers to apply it to their ...
Gilbert, Lester, Sitthisak, Onjira
core  

Educational Priorities of Self-Care Based on Needs Assessment of Household Health Ambassadors [PDF]

open access: yesJournal of Mazandaran University of Medical Sciences
Background and purpose: Self-care is recognized as a fundamental approach in the field of providing, maintaining, and promoting health in individuals, families, and society.
Fatemeh Jafarian   +4 more
doaj  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Rolling out large scale assessment in a training environment

open access: yes, 2012
This paper gives an account of a successful roll-out of a high stakes assessment. Although the target user group size wasn't significant at 10,000 users, the main challenge of the roll out was that it would be managed and delivered by a large number of ...
Steedman, Linda
core  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Towards automatic generation of e-assessment using semantic web technologies

open access: yes, 2011
Semantic web technologies have been increasingly used as a tool for generating, organizing and personalizing e-learning content, including e-assessment.
Tosic, Milorad, Cubric, Marija
core  

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