Results 151 to 160 of about 12,075,699 (303)

Critical care practices in the world: Results of the global intensive care unit need assessment survey 2020. [PDF]

World J Crit Care Med, 2022
Nawaz FA, Deo N, Surani S, Maynard W, Gibbs ML, Kashyap R.   +5 more
europepmc   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Policy Analysis at OTA: A Staff Assessment, May 1993

, 1993
This document presents the findings of the Office of Technology Assessment (OTA) staff assessment of policy analysis that took place in 1992. It consisted of reviewing 18 sample OTA reports and soliciting opinions about OTA's policy analysis from outside
Office of Technology Assessment
core  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

e-Assessment for learning: Can online multiple-choice and extended matching questions really provide useful formative feedback?

, 2012
This article investigates the impact on learning of generic feedback provided automatically after online selected response questions, such as multiple-choice or extended matching questions.
Dermo, John, Carpenter, Liz
core  

UNDERGRADUATE MILITARY MEDICINE – AN ESSENTIAL NEED OF THE PRESENT TIME

Pakistan Armed Forces Medical Journal, 2019
Objective: To assess the need to induct Military Medicine as under graduate subject at military medical colleges of Pakistan. Study Design: Mixed method study.
Shaikh Hussain, Naila Azam, Bashir Ahmed Malik, Rizwan Hashim, Sharafuddin .   +4 more
doaj  

A pandemic that needs assessment

Journal of Healthcare Quality Research, 2020
openaire   +2 more sources

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Orthodontic treatment need assessment and treatment timing - a questionnaire survey among specialists in Denmark and Sweden. [PDF]

Acta Odontol Scand
Rank AN, Sonesson M, Petrén S, Paulsson L, Sonnesen L.   +4 more
europepmc   +1 more source