Results 161 to 170 of about 85,746,451 (299)

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Dystopias: A need for meaning in adolescence

En la actualidad, asistimos a un aumento de las series de televisión y películas que adaptan libros distópicos. Estos son muy apreciados por adolescentes y jóvenes adultos. Tras reflexionar sobre la necesidad de sentido y verdad del individuo, la autora examina hasta qué punto las narraciones distópicas permiten al sujeto pensar las realidades internas
openaire   +1 more source

Death and Injustice: The relationship between mortality salience and just world beliefs on need for meaning

Research using Terror Management Theory (Greenberg et al., 1986; Pyszczynski et al. 2021) demonstrates that existential fears relating to death are coped with and satiated by our self-esteem and cultural worldview.
Wright, Victoria, Arrowood, Robert, Morris, Trevor   +2 more
core  

The Meaning of Establishing and Maintaining a Caring Relationship in the Prehospital Context as Experienced by Specialist Ambulance Nurses. [PDF]

Scand J Caring Sci
Rantala A, Andreasson E, Dahlgren L, Forsberg A.   +3 more
europepmc   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Pedagogical health - a holistic perspective on promoting children's and students' well-being in school. [PDF]

Int J Qual Stud Health Well-being
Ljungblad AL, Hellström L.
europepmc   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

“Virtues and meaning: the relationship between transcendence and meaning in the Mindfulness-Based Strengths Practice protocol”

reservedL’ elaborato ha come oggetto di indagine il protocollo Mindfulness-Based Strengths Practice (MBSP), un training strutturato di otto settimane che combina il costrutto di mindfulness (la capacità di porre attenzione al momento presente in modo ...
MARTINELLI, ALESSIA
core  

Committee For Foreign Need, Hans Burckholder, 3 November 1730

Committee for Foreign Need,
core   +3 more sources

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source