Results 101 to 110 of about 89,629,379 (296)

Students’ Need for Structure—the Forgotten Learning Styles Preference

open access: yes, 2015
The need for structure has not been analyzed to any great extent even though previous research has shown its importance for students. The purpose of this study was therefore to identify, describe, and examine the need for structure among teachers and ...
Gidlund, Ulrika,, Boström, Lena,
core  

A fresh look at the Ramachandran plot and the occurrence of standard structures in proteins

open access: yesBiomolecular Concepts, 2010
The Ramachandran plot is among the most central concepts in structural biology, seen in publications and textbooks alike. However, with the increasing numbers of known protein structures and greater accuracy of ultra-high resolution protein structures ...
Hollingsworth Scott A.   +1 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Mortality Salience, Personal Need for Structure, and the True Self

open access: yes, 2016
Data, study materials, and supplementary results for the paper "The True Self and Existential Structure?
Andrew Christy   +4 more
core  

Structure-Modified Germatranes for Pd-Catalyzed Biaryl Synthesis

open access: yes, 2018
Germanium, a member of 14th group that falls between Si and Sn, has remained considerably ignored as a nucleophile for a long time. Compared with other forms of Ge-containing nucleophiles, germatranes are structure-defined, easily accessible, and ...
Hai-Jie Song (5727569)   +9 more
core   +2 more sources

Needful Structures

open access: yes, 2023
How do humans, their needs, and technology interact in society? Marcel Siegler explores the dialectical relationship between human needs and desires, the demands and requirements of the built world, and the forms of organization that hold both humans and the built world together.
openaire   +4 more sources

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Need for Change Towards the New International Economic Order

open access: yes, 1980
Need for Change: Towards the New International Economic Order represents a selection of speeches given during the period 1974 to early 1980. The speeches are grouped in terms of broad phases or periods in the development of the United Nations Conference ...
Corea, Gamani
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

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