Results 71 to 80 of about 8,016,085 (283)

An Analysis of the Notion of Need for the Representation of Public Services [PDF]

, 2019
Many Public Administrations structure their services around the notion of users’ need. However, there is a gap between private, subjectively perceived needs (self-attributed) and needs that are attributed by PA to citizens ...
Biccheri, Luca, Ferrario, Roberta
core  

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Examining the need for a public procurement maturity model (PPMM) for infrastructure buyers in a monopsony market structure

Romanian Journal of Transport Infrastructure, 2016
This paper examines the need for a Public Procurement Maturity Model (PPMM) in organizations with the role of road infrastructure buyers under public procurement legislation in a monopsony market structure.
Simionescu Violeta
doaj   +1 more source

Exploring the social accountability challenges of nursing education system in Iran

BMC Nursing, 2023
Background Nursing education in Iran is one of the disciplines of medical sciences and it needs a design tailored to the community needs in terms of theoretical and clinical approaches. This system is currently faced with various challenges.
Ebrahim Ezzati, Shahram Molavynejad, Amir Jalali, Mohammad-Ali Cheraghi, Simin Jahani, Dariush Rokhafroz   +5 more
doaj   +1 more source

Structured Evaluation of Virtual Environments for Special-Needs Education [PDF]

Presence: Teleoperators and Virtual Environments, 1999
This paper describes the development of a structured approach to evaluate the experiential and communication virtual learning environments (VLEs) that were designed specifically for use in the education of children with severe learning difficulties at the Shepherd School in Nottingham.
Neale, HR, Brown, DJ, Cobb, SVG, Wilson, JR   +3 more
openaire   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

The need for the solid modelling of structure in the archaeology of buildings

Internet Archaeology, 1997
Three-dimensional modelling is an attempt to represent the world in three dimensions, simplifying through deliberate assumptions. In archaeology, this has developed as an extension of the traditional use of three-dimensional drawings to help present and ...
Robert Daniels
doaj   +1 more source

Structural approaches to understanding retinal proteins needed for vision [PDF]

Current Opinion in Cell Biology, 2014
The past decade has witnessed an impressive expansion of our knowledge of retinal photoreceptor signal transduction and the regulation of the visual cycle required for normal eyesight. Progress in human genetics and next generation sequencing technologies have revealed the complexity behind many inherited retinal diseases.
Orban, Tivadar, Jastrzebska, Beata, Palczewski, Krzysztof   +2 more
openaire   +4 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

The Need for Properly Designed Synthesized Micro- and Nanoplastics with Core–Shell Structure

Microplastics
While there are a number of available reference and testing materials for micro- and nanoplastic (MNP) studies in toxicology, they are not well-characterized and do not cover all major polymer types that may potentially pollute the environment.
Anastasiia Galakhova, Thomas C. Meisel, Gisbert Riess   +2 more
doaj   +1 more source