Results 111 to 120 of about 2,743,843 (310)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Male victims of non-sexual and non-domestic violence: service needs and experiences in court [PDF]
, 2014 This report presents the findings of a study that explored the experiences and support needs of male victims of violence living in New South Wales. Abstract: While a great deal of research has been undertaken into female victims of violence, male ...
Hayley Boxall +2 more
core
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Exploration of training needs assessment methodologies employed by ISO 9000 registered organizations [PDF]
, 1999 Plan BThe purpose of this study is to identify available methods or procedures for determining training needs and to determine which procedures would be appropriate for Northern Engraving Corporation given its culture and internal resources.
Johnson, Edsel J.
core
Needs analysis for public green spaces in Grosuplje [PDF]
Urbani Izziv, 2008 A huge increase in residential and business-commercial construction has characterised Grosuplje, a young town and suburban settlement of the greater Ljubljana area, over the last two decades, thereby increasing the number of possible users of its open ...
Klara Sulič, Ana Kučan
doaj
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
BRIDGING THE GAP BETWEEN NEEDS ANALYSIS AND COURSE EVALUATION INSIGHTS
English Review: Journal of English Education, 2013 The “Advancing English Skills”, textbook was compiled and introduced about a decade ago, at the Faculty of Humanities, Dhaka University, Bangladesh, to teach the foundation English courses, to freshmen students from thirteen departments, including ...
Rubina Khan, Tazin Aziz Chaudhury
doaj
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source