Results 151 to 160 of about 8,424,658 (307)

Biosensors for the Rapid Detection of Cardiovascular Biomarkers of Vital Interest: Needs, Analysis and Perspectives. [PDF]

J Pers Med, 2022
Abensur Vuillaume L, Frija-Masson J, Hadjiat M, Riquier T, d'Ortho MP, Le Borgne P, Goetz C, Voss PL, Ougazzaden A, Salvestrini JP, Leïchlé T.   +10 more
europepmc   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

The needs analysis of the marriage education program for Turkish Cypriot community: Development phase. [PDF]

Front Psychol, 2022
Salman N, Batman KA, Sorakin Y.
europepmc   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Needs Analysis for Non-Face-to-Face Services among Older Adults to Reduce Loneliness. [PDF]

Healthcare (Basel), 2022
Choi HK, Lee SH.
europepmc   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

User Perceptions and Needs Analysis of a Virtual Coach for Active and Healthy Ageing-An International Qualitative Study. [PDF]

Int J Environ Res Public Health, 2022
Möller J, Bevilacqua R, Browne R, Shinada T, Dacunha S, Palmier C, Stara V, Maranesi E, Margaritini A, Takano E, Kondo I, Watanabe S, Ahmadi M, Wieching R, Ogawa T.   +14 more
europepmc   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Limitations in activities of daily living and support needs - Analysis of GEDA 2019/2020-EHIS. [PDF]

J Health Monit, 2022
Fuchs J, Gaertner B, Prütz F.
europepmc   +1 more source

Content needs analysis

, 2023
This thesis presents a comprehensive content needs analysis performed for an e-commerce website. Its objective was to identify the gap between the business objectives and customer needs, utilizing a well-established content needs framework in content strategy.
openaire   +1 more source