Results 201 to 210 of about 2,206,742 (262)

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source
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Training-needs analysis

Learning Disability Practice, 1998
This article introduces training-needs analysis (TNA) and places the process in the broad context of a training strategy. It aims to inform nurses on how the principles of TNA can be applied to their own practice.
openaire   +2 more sources

The Analysis of Need

1983
Publisher Summary Economic psychology is simply the attempt to explore the interconnections between economics and psychology in a systematic way and come up with a coherent interdisciplinary account of the phenomena to be observed at their interface. As an integrated field of study, it does not really exist in the English-speaking world, but it does ...
openaire   +1 more source

Analysis of needs and resources

2016
The initial aim of the CareMan project was to develop a joint degree programme that combined and utilised the strengths of the five collaborating universities that were already involved in delivering social and health care management education.
Vrzáček, Petr   +4 more
openaire   +2 more sources

Needs analysis

CHI '10 Extended Abstracts on Human Factors in Computing Systems, 2010
Needs analysis is a prerequisite to effective design, but typically is difficult and time consuming. We applied and extended our methods and tools in a case study helping a mission control group for the International Space Station. This domain illustrates the challenges of information-system domains that lack rigid, immutable, physical constraints and ...
Dorrit Billman   +3 more
openaire   +1 more source

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