Results 181 to 190 of about 30,536,190 (264)

Culturally Safe Nursing: Transformative Learning Experiences Through Critical Reflection Assessment. [PDF]

Nurs Open
Andrew L, Pedlow M, Ewens B.
europepmc   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Community Relationships and Physician Retention in Clinician Shortage Areas.

JAMA Netw Open
Pathman DE, Schmitz DF, Konrad TR, Rauner TE, Shimmens M.   +4 more
europepmc   +1 more source

Differential effects of social determinants on cancer survival by age at diagnosis: A population-based study in Alabama. [PDF]

J Geriatr Oncol
Fowler ME, Saini G, Baker E, Bhargava M, Aneja R.   +4 more
europepmc   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Nurse-led prehospital obstetric care through the lens of the Three Delays Model: an experience report. [PDF]

Rev Bras Enferm
Britto AMA, Medina ET, Mouta RJO, Silva SCSB.   +3 more
europepmc   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Substitutions affecting the HA-NA-receptor balance preceded the emergence of the pandemic 2009 H1N1 virus. [PDF]

Proc Natl Acad Sci U S A
Marougka K, Leiva-Rebollo R, Hofma F, van Dijk A, Schuurman NNMP, Kaandorp S, Wu X, Liu M, Wallace LE, Chao L, Wennekes T, Uslu E, Boons GJ, den Hertog-Oosterhoff LA, Amatngalim GD, de Vries E, García-Sastre A, de Haan CAM.   +17 more
europepmc   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source