Results 101 to 110 of about 1,047,881 (300)
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source
Educational needs of reproductive health students: A Delphi study
Introduction: The importance of reproductive health led to establish the MSc in reproductive health program in developed country. In Iran, the program has not been offered yet.
N Yamani, M Shakour, S Ehsanpour
doaj
A Critical Insight into Needs Assessment Technique and the Way Social Needs are Actually Assessed
Hamidou Issaka Diori
openalex +2 more sources
Surveying middle school computer science throughout the United States: a needs assessment for teachers [PDF]
Olivia Rose Firth
openalex +1 more source
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Community Living, Intellectual Disability and Extensive Support Needs: A Rights-Based Approach to Assessment and Intervention [PDF]
Laura Esteban +3 more
openalex +1 more source
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source

