Results 111 to 120 of about 8,346,646 (262)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Educational Needs Assessment of Faculty Members of Qom University of Medical Sciences, (Iran)
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2019 Background and Objectives: Since one of the methods of educational needs assessment is self-assessment, thus, it can be useful to determine the training required by professors based on their job descriptions.
Fatemeh Sadat Izadkhah +4 more
doaj
Exploration of training needs assessment methodologies employed by ISO 9000 registered organizations [PDF]
, 1999 Plan BThe purpose of this study is to identify available methods or procedures for determining training needs and to determine which procedures would be appropriate for Northern Engraving Corporation given its culture and internal resources.
Johnson, Edsel J.
core
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The sexual health needs of women within the criminal justice system in Greater Glasgow and Clyde: a health needs assessment [PDF]
, 2017 The aim of the HNA was to systematically describe and measure the sexual health needs of women within the justice system, both incarcerated and in community settings.
Michie, Lucy
core
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Targeted Needs Assessment of Off Service Residents in Emergency Medicine
Western Journal of Emergency Medicine, 2010 Purpose: The purpose of this study is to evaluate the needs of internal medicine residents rotating through the emergency department (ED).Methods: A survey was distributed to 100 internal medicine residents (post-graduate years 2 and 3) from two ...
Kessler, Chad S +2 more
doaj