Results 111 to 120 of about 9,493,025 (351)
Exploration of training needs assessment methodologies employed by ISO 9000 registered organizations [PDF]
, 1999 Plan BThe purpose of this study is to identify available methods or procedures for determining training needs and to determine which procedures would be appropriate for Northern Engraving Corporation given its culture and internal resources.
Johnson, Edsel J.
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Teachers' responses to the emotional needs of children and young people. Results from the Scottish Needs Assessment Programme [PDF]
, 2008 The Scottish Needs Assessment Programme (SNAP) was established in 2000 to advise the Scottish Government on the emotional health of the country's children and young people.
Barbour, R. +14 more
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Health and homelessness needs assessment
, 2002 This report aims to explain and clarify the health needs of the homeless population within Argyll and Clyde by involving service users and the wider community of homeless people. This is placed within the context of existing knowledge and understanding
McMenemy, Barbara +5 more
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FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
, 1986 To conduct a needs assessment of the English Language program at UHM, the systems design approach was adopted to establish goals, objectives, and microskills for two academic listening comprehension courses.
Kimzin, Gail, Poctor, Susan
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Health needs assessment in the contemporary NHS [PDF]
, 1995 Working for Patients, published in January 1989 and the subsequent NHS and Community Care Act 1990, Introduced the most major and complex reorganisation of the NHS since its inception.
Crowe, Patricia Ann
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