Results 101 to 110 of about 9,493,025 (351)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Prison health in NHS Greater Glasgow & Clyde a health needs assessment

open access: yes, 2012
The aim of this Health Needs Assessment (HNA) was to provide a systematic baseline assessment of the health and health care needs of prisoners in NHS Greater Glasgow and Clyde (NHSGGC) and to identify gaps in the current service provision to inform ...
Knifton, Lee   +2 more
core  

Sexual health needs assessment secure care experienced young people

open access: yes, 2021
Systemically describe and measure sexual health needs of secure CE-YP in NHS Scotland. This will evaluate the current service and inform future plans to design and deliver appropriate patient centred sexual health care to secure CE ...
Simpson, Janine
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Carers needs assessment: analysis of the findings report and areas for action

open access: yes, 2012
A carer’s needs assessment was developed to explore the needs of carers attending Yorkhill hospital with their children. It was recognised that Out Patients Department within Yorkhill was a starting point to consider exploring what carers need in a ...
Nish, Lesley
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Extent, nature and causes of homelessness in Glasgow : a needs assessment

open access: yes, 2003
The purpose of this needs assessment is to provide a public health perspective on homeless people in Glasgow that will for the basis for rational planning and organisation of services, identifying the most effective ...
Morrison, David
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Trauma informed practice training needs assessment: final report and supporting action plan

open access: yes, 2018
In 2017, Rocket Science in partnership with the University of St Andrews was commissioned to complete a Trauma Informed Practice training needs assessment on a range of services in the West of Scotland. The Glasgow City, East Renfrewshire, Inverclyde and
Hammond, Clare, Gardner, Paul
core  

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