Results 61 to 70 of about 68,756 (292)

Effects of different negative pressure wound therapy modes on wound healing: a systematic review

Frontiers in Medicine
IntroductionNegative pressure wound therapy (NPWT) has been widely used in wound care, yet the optimal application mode—continuous, intermittent, or dynamic—remains unclear.
Cuiyi Wang, Xing Liu, Yitao Zhou, Naqin Liu, Yeqin Yang   +4 more
doaj   +1 more source

Effect of negative pressure wound therapy on wound healing

Current Problems in Surgery, 2014
The efficacy of NPWT in promoting wound healing has been largely accepted by clinicians, yet the number of high-level clinical studies demonstrating its effectiveness is small and much more can be learned about the mechanisms of action. In the future, hopefully we will have the data to assist clinicians in selecting optimal parameters for specific ...
Huang, Chenyu, Leavitt, Tripp, Bayer, Lauren, Orgill, Dennis   +3 more
openaire   +4 more sources

Negative pressure wound therapy with instillation (NPWTi): Current status, recommendations and perspectives in the context of modern wound therapy.

, 2016
Introduction of negative pressure wound therapy (NPWT) revolutionized the conception of wound healing. Currently, there are an increased number of studies confirmed the high efficiency of this therapy in many clinical scenarios.
Drews, Michał, Banasiewicz, Tomasz, Bobkiewicz, Adam, Studniarek, Adam   +3 more
core   +1 more source

Impact of negative pressure wound therapy and nanocrystalline silver dressings on the quality of life of patients with chronic non-healing ulcers: a preliminary study

, 2022
Therapeutic measures should be primarily directed to promote healing, but also to improve or at least to maintain HRQoL. This prospective randomized pilot study was conducted to assess the impact on HRQoL of negative pressure wound therapy (NPWT ...
García-Martínez, Lourdes, Pérez-Ferriols, Amparo, Román-Curto, Concepción, Sáez-Martín, Luis C.   +3 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Negative pressure wound therapy in the treatment of surgical site infection in cardiac surgery [PDF]

Revista Brasileira de Enfermagem
Objectives: to describe the relationship between epidemiological and clinical characteristics of postoperative cardiac surgery patients undergoing negative pressure wound therapy for the treatment of surgical site infection.
Mayra de Castro Oliveira, Alessandra Yuri Takehana de Andrade, Ruth Natalia Teresa Turrini, Vanessa de Brito Poveda   +3 more
doaj   +4 more sources

Evidence update on prevention of surgical site infection [PDF]

, 2015
Purpose of review: surgical site infection (SSI) is a common health care associated infection and complicates up to 10-20% of operations with considerable health care resources.
Leaper, David J., Ousey, Karen, Leaper, David   +2 more
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Instillation-TIME (iTIME) as a rationale amendment for TIME conception. Is there enough evidence for the efficiency of negative pressure wound therapy with instillation (iNPWT) to announce a breakthrough idea for wound treatment?

, 2019
An increased number of patients developing difficult-to-heal wounds results in billions spending for chronic wound care management. Introduction of TIME conception has been a breakthrough idea for wound healing based on phase-adapted wound therapy that ...
Drews, Michał, Banasiewicz, Tomasz, Bobkiewicz, Adam, Studniarek, Adam, Krokowicz, Łukasz   +4 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source