Results 101 to 110 of about 16,033,070 (295)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Quantifying the distinct role of plasmon enhancement mechanisms in prototypical antenna-reactor photocatalysts

Nature Communications
Plasmonic photocatalysis enabled by the unique localized surface plasmon resonance represents a promising approach for efficient solar energy conversion.
Shuang Liu, Zhiyi Wu, Zhijie Zhu, Kai Feng, Yuxuan Zhou, Xinge Hu, Xiong Huang, Binbin Zhang, Xudong Dong, Yueru Ma, Kaiqi Nie, Jiahui Shen, Zidi Wang, Jiari He, Jiaqi Wang, Yu Ji, Binhang Yan, Qingfeng Zhang, Alexander Genest, Xiaohong Zhang, Chaoran Li, Bo Wu, Xingda An, Günther Rupprechter, Le He   +24 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Highly Suspected COVID-19 Cluster with Multiple Negative SARS-CoV-2 RNA Tests: A Case Report

Infection and Drug Resistance, 2021
Xialing Huang,1 Xiaoping Long,2 Jun Zi,3 Ping Liu4 1Department of Infectious Diseases, Leiyang People’s Hospital, Leiyang, Hunan, 421800, People’s Republic of China; 2Pulmonary and Critical Care Medicine, The First Affiliated Hospital of University of ...
Huang X, Long X, Zi J, Liu P
doaj  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Breathing mode in Nd-CoOx for active and stable proton exchange membrane water electrolysis

Nature Communications
Proton-exchange membrane water electrolysis in acidic solutions holds great promise for advancing the green-hydrogen economy but limited by using precious-metal catalysts.
Yong Feng, Jianhua Wang, Kun Feng, Bai Xu, Jiabin Xu, Shuo Li, Cheng Lu, Xing Fan, Haiping Lin, Jun Zhong   +9 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Structural types of sentences in Kosovo police communication centers

Comparative Legilinguistics
In this paper it will be analyzed grammatical and dialectal aspect of structural sentences of Albanian language used in six Kosovo Police Communication Centers.
Shemsi Haziri, Senad Neziri
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source