Results 231 to 240 of about 11,122,835 (315)

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Updated Testing Sensitivities and Variants of Uncertain Significance in CanRisk

Easton DF, Carver T, Ficorella L, Hanson H, Snape K, Tsoulaki O, Usher-Smith JA, Archer S, Tischkowitz M, Antoniou A.   +9 more
europepmc   +1 more source

Media News Engagement and Parent-Child Well-being during Regional Conflict: A Daily Diary Study. [PDF]

Res Child Adolesc Psychopathol
Dann Y, Gueron-Sela N.
europepmc   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Negative religious coping is associated with fear of childbirth and pregnancy distress: findings from correlational and regression analyses. [PDF]

Rev Assoc Med Bras (1992)
Öçal SE, Çetinkaya ŞŞ.
europepmc   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Intraoperative Urine Tests and STONE Score Predict Postoperative SIRS (Systemic Inflammatory Response Syndrome) After PCNL in Patients with Negative Preoperative Urine Culture. [PDF]

Int J Gen Med
Wen J, Liu C, Lu K, Chen W, Gao R.
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Synovial Fluid Cell Profiling Identifies Distinct Inflammatory Phenotypes in Late-Onset Rheumatoid Arthritis and Polymyalgia Rheumatica. [PDF]

ACR Open Rheumatol
Tanaka S, Sugiyama T, Kameda S, Takahashi T, Yasui M, Hayashi Y, Ida T, Yoshida Y, Kubota S, Ito T, Kageyama T, Nakagomi D, Ikeda K, Kagami SI, Nakajima H.   +14 more
europepmc   +1 more source