Results 111 to 120 of about 4,299,342 (207)

Dysfunctional Cognitions: Associations with Perfectionistic Thinking Utilizing the Positive and Negative Perfectionism Construct [PDF]

open access: yes, 2004
Historically, perfectionism has been associated with symptomatologies such as depression, anxiety, and procrastination (Hewitt & Flett, 1991). However, a newer construct expands and includes both positive and negative aspects to perfectionism (Flett ...
Nyland, Jennifer E.
core  

RG 0770.000.000 Fort Delaware Glass Negative Collection

open access: yes, 1898
Fort Mott? (Negative blurred) No label. 12'' B. L.
U. S. Corps of Engineers
core   +3 more sources

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

The Negative Effects of Student Mobility: Mobility as a Predictor, Mobility as a Mediator

open access: yesInternational Journal of Education Policy and Leadership, 2013
Policy discussions on how to improve educational outcomes have traditionally focused on schools and teachers. While schools and teachers have measurable effects on educational outcomes, reforms aimed at only improving schools and teachers have failed to ...
Jimmy Scherrer
doaj  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Negative variance estimates in panel data models [PDF]

open access: yes
Negative values for estimated variances can arise in a panel data context. Empirical and theoretical literature dismisses the problem as not serious and a practical solution is to replace negative variances by its boundary value, i.e. zero. While this is
Laura Magazzini, Giorgio Calzolari
core  

Analyzing emotion in Project Management

open access: yesDyna
This article analyzes different ways emotions have been studied and applied to promote better communication and working conditions, leading to more successful projects and helping build stronger relationships between members. Project management relies on
Cynthia M. Montaudon-Tomas   +2 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

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