Results 131 to 140 of about 16,277,273 (324)

The Negative Effects of Student Mobility: Mobility as a Predictor, Mobility as a Mediator

International Journal of Education Policy and Leadership, 2013
Policy discussions on how to improve educational outcomes have traditionally focused on schools and teachers. While schools and teachers have measurable effects on educational outcomes, reforms aimed at only improving schools and teachers have failed to ...
Jimmy Scherrer
doaj  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Negative results [PDF]

Nature, 2008
openaire   +4 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Analyzing emotion in Project Management

Dyna
This article analyzes different ways emotions have been studied and applied to promote better communication and working conditions, leading to more successful projects and helping build stronger relationships between members. Project management relies on
Cynthia M. Montaudon-Tomas, Anna Amsler, Ingrid N. Pinto-López   +2 more
doaj   +1 more source

Large negative linear compressibility of Ag ₃ [Co(CN) ₆ ]

, 2008
Andrew L. Goodwin, David A. Keen, Matthew G. Tucker   +2 more
openalex   +2 more sources

In vivo CRISPR screens identify RhoV as a pro‐metastasis factor of triple‐negative breast cancer [PDF]

, 2023
Ming‐Liang Jin, Yue Gong, Peng Ji, Xin Hu, Zhi‐Ming Shao   +4 more
openalex   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Negative banner [PDF]

British Dental Journal, 2009
openaire   +2 more sources