Results 191 to 200 of about 16,277,273 (324)

Pertinent Negatives [PDF]

Journal of General Internal Medicine, 2021
openaire   +2 more sources

Positive and Negative Regulation of Gli Activity by Kif7 in the Zebrafish Embryo

, 2013
Ashish K. Maurya, Jin Ben, Zhonghua Zhao, Raymond Teck Ho Lee, Weixin Niah, Ashley Shu Mei Ng, Audrey Iyu, Weimiao Yu, Stone Elworthy, Fredericus J. M. van Eeden, Philip W. Ingham   +10 more
openalex   +2 more sources

Structural assignment of isomeric 2‐aminopyridine‐derivatized monosialylated biantennary N‐linked oligosaccharides using negative‐ion multistage tandem mass spectral matching [PDF]

, 2005
Kisaburo Deguchi, Yasuhiro Takegawa, Hiroki Ito, Nobuaki Miura, Shinji Yoshioka, Shinji Nagai, Hiroaki Nakagawa, Shin‐Ichiro Nishimura   +7 more
openalex   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Maternal Milk Allopregnanolone May Buffer Negative Associations Between Maternal Postpartum Psychological Distress and Infant Regulatory Capacity. [PDF]

Dev Psychobiol
Werchan DM, Susskind B, Carpio R, Howell BR, Brito NH, Thomason ME.   +5 more
europepmc   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

A Buffered LC-MS Method for Resolving and Quantifying Albiflorin and Paeoniflorin. [PDF]

Biomed Chromatogr
Gazizova A, Altincubuk EH, Oppermann C.
europepmc   +1 more source

Resonant light scattering by small coated nonmagnetic spheres: magnetic resonances, negative refraction, and prediction

, 2008
Cheng‐Wei Qiu, Lei Gao
openalex   +2 more sources

ANCA-Negative Wegener's Granulomatosis with Multiple Lower Cranial Nerve Palsies [PDF]

, 2013
Sung-Hee Kim, Jin Park, Jung Ho Bae, Min-Sun Cho, Kee Duk Park, Jee Hyang Jeong   +5 more
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source