Results 111 to 120 of about 4,148,085 (257)

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Highly Suspected COVID-19 Cluster with Multiple Negative SARS-CoV-2 RNA Tests: A Case Report

open access: yesInfection and Drug Resistance, 2021
Xialing Huang,1 Xiaoping Long,2 Jun Zi,3 Ping Liu4 1Department of Infectious Diseases, Leiyang People’s Hospital, Leiyang, Hunan, 421800, People’s Republic of China; 2Pulmonary and Critical Care Medicine, The First Affiliated Hospital of University of ...
Huang X, Long X, Zi J, Liu P
doaj  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Quantifying the distinct role of plasmon enhancement mechanisms in prototypical antenna-reactor photocatalysts

open access: yesNature Communications
Plasmonic photocatalysis enabled by the unique localized surface plasmon resonance represents a promising approach for efficient solar energy conversion.
Shuang Liu   +24 more
doaj   +1 more source

Necros, Negative Approach and Meatmen concert flier, Freezer Theatre, Detroit, MI, April 3, 1982

open access: yes, 1982
2015 photocopy from back of letter dated April 19, 1982 sent to Sharon Cheslow by Barry Henssler of a flier published in the "Smegma Journal" fanzine.

core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Structural types of sentences in Kosovo police communication centers

open access: yesComparative Legilinguistics
In this paper it will be analyzed grammatical and dialectal aspect of structural sentences of Albanian language used in six Kosovo Police Communication Centers.
Shemsi Haziri, Senad Neziri
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

WHEN DOES NEGATIVE BRAND PUBLICITY HURT? The Moderating Influence of Analytic Versus Holistic Thinking [PDF]

open access: yes
Negative publicity can diminish positive consumer perceptions of a brand. We explore the impact of processing style on mitigating the effects of negative publicity.
Alokparna (Sonia) Basu Monga   +1 more
core  

Licensing german negative polarity items in LTAG [PDF]

open access: yes, 2008
Our paper aims at capturing the distribution of negative polarity items (NPIs) within lexicalized Tree Adjoining Grammar (LTAG). The condition under which an NPI can occur in a sentence is for it to be in the scope of a negation with no quantifiers ...
Lichte, Timm, Kallmeyer, Laura
core  

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