Results 101 to 110 of about 9,958,990 (309)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
WHEN DOES NEGATIVE BRAND PUBLICITY HURT? The Moderating Influence of Analytic Versus Holistic Thinking [PDF]
Negative publicity can diminish positive consumer perceptions of a brand. We explore the impact of processing style on mitigating the effects of negative publicity.
Alokparna (Sonia) Basu Monga +1 more
core
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Simultaneous non-negative matrix factorization for multiple large scale gene expression datasets in toxiciology [PDF]
, 2012 Non-negative matrix factorization is a useful tool for reducing the dimension of large datasets. This work considers simultaneous non-negative matrix factorization of multiple sources of data.
Mudaliar, Manikhandan A. V. +7 more
core +2 more sources
Drug Design, Development and Therapy, 2018 Barbara Lisowska,1 Dariusz Kosson,2 Karolina Domaracka3 1Department of Anesthesiology and Intensive Care, John Paul II Western Hospital, Grodzisk Mazowiecki, Poland; 2Department of Anaesthesiology and Intensive Care, Medical University of Warsaw ...
Lisowska B, Kosson D, Domaracka K
doaj
“Tıbâk” [Tezat] Sanatı Bağlamında Kur’an’da Optimizm
İlahiyat Tetkikleri Dergisi, 2017 Vahiy Menşeli Kutsal Metinlerin pek çok edebî sanatı bir anlatım üslûbu olarak benimsediğibilinmektedir. Bu üslûp yapılanması o metinlere efsunkâr bir ifade gücü kazandırmaktadır.Çalışma, edebî sanat türlerinden biri olan “tıbâk” [tezat] sanatı dâhilinde
Necdet Çağıl
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The ‘mound-hollow’ model for solving integer addition and subtraction problems
Journal on Mathematics EducationUnderstanding integer operations is a fundamental yet challenging concept for elementary students, often requiring effective visual models to support their comprehension.
Puspita Sari +2 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Negative symptoms in neuroleptic-naïve patients with first-episode psychosis correlate with QEEG parameters [PDF]
, 2009 INTRODUCTION: While several studies have shown an association of QEEG band power with negative symptoms in patients with schizophrenia, this has not yet been investigated in a sample with neuroleptic-naïve first-episode patients (NNFE) up to now.
Peter Fuhr +14 more
core +1 more source