Results 231 to 240 of about 9,958,990 (309)

Parenting as a moderator of the neural mechanisms between irritability and inhibition in young children. [PDF]

J Mood Anxiety Disord
Duran AN, Medina V, Dougherty LR, Wiggins JL.   +3 more
europepmc   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Clinical Utility of 18F-FDG PET/CT for Staging and Restaging of Pediatric Malignant Melanoma: A Single-Center Retrospective Study. [PDF]

Children (Basel)
Isik EG, Kebudi R.
europepmc   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

From SELEX to sequencing: uncovering enriched aptamers with next-generation sequencing and bioinformatics. [PDF]

Bioinformatics
Girbas MG, Müller J, Schlensak C, Avci-Adali M.   +3 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Patterns of attentional and recognition-memory processing of emotional information among Chinese middle school students with different exercise volumes. [PDF]

BMC Psychol
Chen K, Wang P.
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Serum Free Fatty Acid-Based Diagnostic Index for Cervical Cancer Including High-Risk HPV-Negative Cases: An Independent Validation Study. [PDF]

Diagnostics (Basel)
Katoh Y, Fujii Y, Yamazaki N, Kubo A, Kamata S, Okuma Y, Yang T, Futatsugi A, Sakamoto M, Hino H, Ogawa T, Fukuta M, Iwata T, Nishio H, Sugawara M, Kawana K, Hirai S.   +16 more
europepmc   +1 more source