Results 161 to 170 of about 14,118,684 (408)

Is negative affectivity associated with oral quality of life? [PDF]

open access: bronze, 2001
Nancy R. Kressin   +3 more
openalex   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Serotonin Transporter Promoter Polymorphism Genotype Is Associated With Behavioral Disinhibition and Negative Affect in Children of Alcoholics [PDF]

open access: green, 2001
Geoffrey R. Twitchell   +5 more
openalex   +1 more source

Negative affect interacts with perceptual affective biases

open access: yes
BackgroundAffective biases are central to mood and anxiety disorders, with individuals often interpreting ambiguous facial expressions more negatively. Adaptation paradigms - where exposure to emotional stimuli shifts perception - offer a tool to separate perceptual from decisional biases, but have not yet been used to study emotional biases in ...
Thomas Murray, Rebecca Lawson
openaire   +1 more source

Relationships between coping strategies and mood states in caregivers of people with dementia in New Zealand : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Psychology at Massey University [PDF]

open access: yes, 2004
Alzheimer's dementia is a worldwide concern, as is the growing aging population and demands on services by many elderly people. Caregiving for people with dementia is recognised as one of the most distressing events in any family's life cycle.
Dominy, Jean Beatrice
core  

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

open access: yesMolecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song   +11 more
wiley   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

open access: yesMolecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton   +17 more
wiley   +1 more source

Home - About - Disclaimer - Privacy