Results 61 to 70 of about 2,274,380 (266)

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Investigation Of The Prevalence Of Musculoskeletal Disorders And Its Relationship With Negative Affect In Nurses: A Descriptive-Analytical Study

طب کار, 2021
Background and Aim: The effect of musculoskeletal disorders and its association with negative affect in nurses has been less studied; Due to the need to find practical factors in preventing musculoskeletal disorders, the present study conducted to ...
Khalil BorhanZehi, Zahra Ebrahimi rigi, Elnaz YazdanParast, Saiede Dadpishe, Hajare Ebrahimi rigi   +4 more
doaj  

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Positive and Negative Affect and Eating Behavior Among Adults: The Mediating Role of Emotion Regulation

Brain Sciences
Background: Emotions substantially influence human eating behavior, but while negative affect has been consistently associated with maladaptive eating patterns, the role of positive affect remains underexplored.
Despoina Kourtidi, Evangelos Ntouros, Agorastos Agorastos   +2 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Escala de afeto positivo e negativo para crianças: estudos de construção e validação

Psicologia Escolar e Educacional
O objetivo deste estudo foi desenvolver uma Escala de Afeto Positivo e Negativo para Crianças. São apresentados dois estudos: de construção da escala, bem como de validação concorrente. Além disso, procurou-se avaliar o nível de afeto positivo e negativo
Claudia Hofheinz Giacomoni, Cláudio Simon Hutz   +1 more
doaj  

Correction to: Coffee cover surrounding forest patches negatively affect Euglossini bee communities [PDF]

, 2022
Lázaro da Silva Carneiro, Wilson Frantine‐Silva, Willian Moura de Aguiar, Gabriel A. R. Melo, Milton Cézar Ribeiro, Silvia Helena Sofia, Maria Cristina Gaglianone   +6 more
openalex   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Ugly Book Feelings: Materiality and Negative Affect in Late Medieval Women’s Writing [PDF]

, 2023
Stephanie Downes, Stephanie Trigg
openalex   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source