Results 71 to 80 of about 5,810,520 (359)

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

An Exploration of Resilience and Positive Affect among Undergraduate Nursing Students: A Longitudinal Observational Study

open access: yesNursing Reports
Background: The purpose of this study is to analyze the variation in resilience and emotional state scores in nursing students throughout the four years of training for the nursing degree.
L. Iván Mayor-Silva   +3 more
doaj   +1 more source

Correlational study between negative affect and school refusal [PDF]

open access: yes, 2016
El estudio del afecto y su relación con el comportamiento de rechazo a la escuela es un campo de investigación con escasos trabajos previos. El objetivo de estudio fue analizar la relación entre el Afecto Negativo y los distintos factores que justifican ...
García-Fernández, José Manuel   +4 more
core   +4 more sources

The intracellular domain of TLR2 is capable of high‐affinity Zn binding: possible outcomes for the receptor activation

open access: yesFEBS Letters, EarlyView.
Toll‐like receptors (TLRs) are important in the innate immune system. This study explores the zinc‐binding ability of the TLR2 TIR domain (TLR2TIR). We found that TLR2TIR binds zinc with nanomolar affinity through its cysteine residues. Two of them, C673 and C713, are vital for receptor activation, indicating that zinc may play a role in initiating ...
Vladislav A. Lushpa   +8 more
wiley   +1 more source

Personal projects, affect, and need satisfaction : a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in psychology, at Massey University [PDF]

open access: yes, 1992
The present study investigated effects that patterns of purposeful human action, conceived as personal projects, have on positive and negative affect and need satisfaction.
Ballantyne, Jonathan Thomas
core  

Aging is associated with positive responding to neutral information but reduced recovery from negative information [PDF]

open access: yes, 2011
Studies on aging and emotion suggest an increase in reported positive affect, a processing bias of positive over negative information, as well as increasingly adaptive regulation in response to negative events with advancing age.
Angrilli   +56 more
core   +3 more sources

The Effect of a Maternal Mediterranean Diet in Pregnancy on Insulin Resistance is Moderated by Maternal Negative Affect. [PDF]

open access: yes, 2020
There is inconsistent evidence that healthy dietary interventions can effectively mitigate the risk of adverse outcomes associated with elevated insulin resistance in pregnancy, suggesting that other moderating factors may be at play.
Buss, Claudia   +3 more
core   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

Valence-specific EEG microstate modulations during self-generated affective states

open access: yesFrontiers in Psychology
IntroductionThis study aims to explore the temporal dynamics of brain networks involved in self-generated affective states, specifically focusing on modulating these states in both positive and negative valences.
Karina Nazare   +3 more
doaj   +1 more source

Perceived Maternal Invalidation and Drinking Behavior: The Role of Action Control [PDF]

open access: yes, 2018
Alcohol use disorder is one of the most prevalent disorders worldwide. As such, researchers have examined factors contributing to alcohol use. Perception of emotional experiences in childhood as invalidating by parents is one factor that has been found ...
Warner, Elise Ann
core   +2 more sources

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