Making tau amyloid models in vitro: a crucial and underestimated challenge
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Background: The purpose of this study is to analyze the variation in resilience and emotional state scores in nursing students throughout the four years of training for the nursing degree.
L. Iván Mayor-Silva+3 more
doaj +1 more source
Correlational study between negative affect and school refusal [PDF]
El estudio del afecto y su relación con el comportamiento de rechazo a la escuela es un campo de investigación con escasos trabajos previos. El objetivo de estudio fue analizar la relación entre el Afecto Negativo y los distintos factores que justifican ...
García-Fernández, José Manuel+4 more
core +4 more sources
Toll‐like receptors (TLRs) are important in the innate immune system. This study explores the zinc‐binding ability of the TLR2 TIR domain (TLR2TIR). We found that TLR2TIR binds zinc with nanomolar affinity through its cysteine residues. Two of them, C673 and C713, are vital for receptor activation, indicating that zinc may play a role in initiating ...
Vladislav A. Lushpa+8 more
wiley +1 more source
Personal projects, affect, and need satisfaction : a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in psychology, at Massey University [PDF]
The present study investigated effects that patterns of purposeful human action, conceived as personal projects, have on positive and negative affect and need satisfaction.
Ballantyne, Jonathan Thomas
core
Aging is associated with positive responding to neutral information but reduced recovery from negative information [PDF]
Studies on aging and emotion suggest an increase in reported positive affect, a processing bias of positive over negative information, as well as increasingly adaptive regulation in response to negative events with advancing age.
Angrilli+56 more
core +3 more sources
The Effect of a Maternal Mediterranean Diet in Pregnancy on Insulin Resistance is Moderated by Maternal Negative Affect. [PDF]
There is inconsistent evidence that healthy dietary interventions can effectively mitigate the risk of adverse outcomes associated with elevated insulin resistance in pregnancy, suggesting that other moderating factors may be at play.
Buss, Claudia+3 more
core +1 more source
The power of microRNA regulation—insights into immunity and metabolism
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto+2 more
wiley +1 more source
Valence-specific EEG microstate modulations during self-generated affective states
IntroductionThis study aims to explore the temporal dynamics of brain networks involved in self-generated affective states, specifically focusing on modulating these states in both positive and negative valences.
Karina Nazare+3 more
doaj +1 more source
Perceived Maternal Invalidation and Drinking Behavior: The Role of Action Control [PDF]
Alcohol use disorder is one of the most prevalent disorders worldwide. As such, researchers have examined factors contributing to alcohol use. Perception of emotional experiences in childhood as invalidating by parents is one factor that has been found ...
Warner, Elise Ann
core +2 more sources