Results 91 to 100 of about 49,117 (256)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Background: Akara, Ukara, Makara (OUM) chanting regulates emotions and removes negative emotions by inactivating the processing in the amygdala. At the same time, the prefrontal complex was inhibited followed by chanting OUM.
Deepa Chokkan +3 more
doaj +1 more source
Job insecurity, burnout and work engagement: The impact of positive and negative affectivity
The objective of this study was to investigate the relationship between job insecurity, affectivity, burnout and work engagement of employees (N = 297) in a government organisation. A cross-sectional survey design was used.
J Bosman, S Rothmann, J H Buitendach
doaj +1 more source
Depresión y ansiedad en mujeres con cáncer de mama: el papel de la afectividad y el soporte social [PDF]
OBJECTIVE: To establish the relationship between affectivity and social support profile and the presence and severity of depression and anxiety among women with breast cancer.
Jiménez, Luz Margarita +3 more
core +1 more source
The relevance of schizotypal traits for understanding interpersonal functioning in adolescents with psychiatric problems. [PDF]
A
De Clercq, Barbara +4 more
core +2 more sources
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Dispositional Influences on Attributions Concerning Absenteeism [PDF]
Because the degree to which absenteeism is within or beyond an employee\u27s control is a significant yet unresolved issue in the absence literature, it is important to understand the factors which influence employees\u27 attributions about the causes of
Judge, Timothy A. +1 more
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
The Effect of Dysfunctional Thought Processes on Subjective Well-Being and Job Satisfaction [PDF]
While the dispositional approach to job satisfaction has received a good deal of recent attention, a fundamental deficiency in past dispositional research is a failure to use existing theories to explain why individuals are unhappy and dissatisfied with ...
Judge, Timothy A., Locke, Edwin A.
core +1 more source

